Guanine Nucleotide Binding Protein Beta Polypeptide 3 Recombinant Protein | GNB3 recombinant protein
Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 3
Purity
Greater than 80.0% as determined by SDS-PAGE.
Synonyms
Guanine Nucleotide Binding Protein Beta Polypeptide 3; Recombinant Human Guanine Nucleotide Binding Protein Beta Polypeptide 3; GNB3 Human; Guanine Nucleotide Binding Protein Beta Polypeptide 3 Human Recombinant; Transducin Beta Chain 3; G Protein; Beta-3 Subunit; GTP-Binding Regulatory Protein Beta-3 Chain; Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 3; Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-3; Hypertension Associated Protein; Guanine Nucleotide Binding Protein (G Protein); Beta Polypeptide 3; GNB3; GNB3 recombinant protein
Host
E Coli
Purity/Purification
Greater than 80.0% as determined by SDS-PAGE.
Form/Format
GNB3 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.4M Urea.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMGEMEQL RQEAEQLKKQ IADARKACAD VTLAELVSGL EVVGRVQMRT RRTLRGHLAK IYAMHWATDS KLLVSASQDG KLIVWDSYTT NKVHAIPLRS SWVMTCAYAP SGNFVACGGL DNMCSIYNLK SREGNVKVSR ELSAHTGYLS CCRFLDDNNI VTSSGDTTCA LWDIETGQQK TVFVGHTGDC MSLAVSPDFN LFISGACDAS AKLWDVREGT CRQTFTGHES DINAICFFPN GEAICTGSDD ASCRLFDLRA DQELICFSHE SIICGITSVA FSLSGRLLFA GYDDFNCNVW DSMKSERVGI LSGHDNRVSC LGVTADGMAV ATGSWDSFLK IWN
Sequence Length
339
Related Product Information for GNB3 recombinant protein
Description: GNB3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 363 amino acids (1-340 a.a) and having a molecular mass of 39.6kDa.GNB3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: GNB3 belongs to the WD repeat G protein beta family. GNB3 is an important regulator of alpha subunit, as well as of certain signal transduction receptor and effector. A single-nucleotide polymorphism (C825T) in GNB3 is linked with essential hypertension and obesity. In addition, this polymorphism is also linked with the occurrence of the splice variant GNB3-s, which seems to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Further splice variants may exist for GNB3, however they have not been fully described. Among the diseases associated with GNB3 are syncope, and aortic coarctation.
Introduction: GNB3 belongs to the WD repeat G protein beta family. GNB3 is an important regulator of alpha subunit, as well as of certain signal transduction receptor and effector. A single-nucleotide polymorphism (C825T) in GNB3 is linked with essential hypertension and obesity. In addition, this polymorphism is also linked with the occurrence of the splice variant GNB3-s, which seems to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Further splice variants may exist for GNB3, however they have not been fully described. Among the diseases associated with GNB3 are syncope, and aortic coarctation.
Product Categories/Family for GNB3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,633 Da
NCBI Official Full Name
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 2
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein), beta polypeptide 3
NCBI Official Symbol
GNB3
NCBI Protein Information
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; G protein, beta-3 subunit; GTP-binding regulatory protein beta-3 chain; guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 3; hypertension associated protein; transducin beta chain 3
UniProt Protein Name
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
UniProt Gene Name
GNB3
UniProt Entry Name
GBB3_HUMAN
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Product Notes
The GNB3 gnb3 (Catalog #AAA142887) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMGE MEQL RQEAEQLKKQ IADARKACAD VTLAELVSGL EVVGRVQMRT RRTLRGHLAK IYAMHWATDS KLLVSASQDG KLIVWDSYTT NKVHAIPLRS SWVMTCAYAP SGNFVACGGL DNMCSIYNLK SREGNVKVSR ELSAHTGYLS CCRFLDDNNI VTSSGDTTCA LWDIETGQQK TVFVGHTGDC MSLAVSPDFN LFISGACDAS AKLWDVREGT CRQTFTGHES DINAICFFPN GEAICTGSDD ASCRLFDLRA DQELICFSHE SIICGITSVA FSLSGRLLFA GYDDFNCNVW DSMKSERVGI LSGHDNRVSC LGVTADGMAV ATGSWDSFLK IWN. It is sometimes possible for the material contained within the vial of "Guanine Nucleotide Binding Protein Beta Polypeptide 3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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