Rat glucocorticoid modulatory element binding protein 1 ELISA Kit | GMEB1 elisa kit
Rat Glucocorticoid modulatory element-binding protein 1, GMEB1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
GMEB1: Trans-acting factor that binds to glucocorticoid modulatory elements (GME) present in the TAT (tyrosine aminotransferase) promoter and increases sensitivity to low concentrations of glucocorticoids. Binds also to the transferrin receptor promoter. Essential auxiliary factor for the replication of parvoviruses. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor co-regulator
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: DNA binding; metal ion binding; transcription coactivator activity; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter