Glutaminase kidney isoform, mitochondrial Recombinant Protein | Gls recombinant protein
Recombinant Rat Glutaminase kidney isoform, mitochondrial
Gene Names
Gls; Glut; RATGLUT
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Glutaminase kidney isoform; mitochondrial; Recombinant Rat Glutaminase kidney isoform; K-glutaminase L-glutamine amidohydrolase Cleaved into the following 2 chains: 1. Glutaminase kidney isoform 68 kDa chain 2. Glutaminase kidney isoform 65 kDa chain; Gls recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
17-674, Full Length of Mature Protein
Sequence
PPAAVGGVLRRTQPLGTLCRRPRGGSRPAAGLVAAARLHPWWGGGGRAKGPGSGGLSSSPSEILQELGKGGTPPQQQQQQQQQPGASPPAAPGPKDSPGETDAFGNSEGKEMVAAGDNKVKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKECMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELYESAKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAVNDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDYVMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQLCSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFAKKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEGHVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDDGKENQTVHKNLDGLL
Sequence Length
658
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Gls recombinant protein
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain.
Product Categories/Family for Gls recombinant protein
References
"Isolation, characterization, and in vitro expression of a cDNA that encodes the kidney isoenzyme of the mitochondrial glutaminase." Shapiro R.A., Farrell L., Srinivasan M., Curthoys N.P. J. Biol. Chem. 266:18792-18796(1991)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
88.4kD
NCBI Official Full Name
glutaminase kidney isoform, mitochondrial isoform b
NCBI Official Synonym Full Names
glutaminase
NCBI Official Symbol
Gls
NCBI Official Synonym Symbols
Glut; RATGLUT
NCBI Protein Information
glutaminase kidney isoform, mitochondrial
UniProt Protein Name
Glutaminase kidney isoform, mitochondrial
Protein Family
UniProt Gene Name
Gls
UniProt Synonym Gene Names
GLS
NCBI Description
catalyzes the conversion of L-glutamine and H2O to L-glutamate and NH3 in glutamine catabolism [RGD, Feb 2006]
Uniprot Description
Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain.
Research Articles on Gls
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Product Notes
The Gls gls (Catalog #AAA967064) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 17-674, Full Length of Mature Protein. The amino acid sequence is listed below: PPAAVGGVLR RTQPLGTLCR RPRGGSRPAA GLVAAARLHP WWGGGGRAKG PGSGGLSSSP SEILQELGKG GTPPQQQQQQ QQQPGASPPA APGPKDSPGE TDAFGNSEGK EMVAAGDNKV KQGLLPSLED LLFYTIAEGQ EKIPVHKFIT ALKSTGLRTS DPRLKECMDM LRLTLQTTSD GVMLDKDLFK KCVQSNIVLL TQAFRRKFVI PDFMSFTSHI DELYESAKKQ SGGKVADYIP QLAKFSPDLW GVSVCTVDGQ RHSIGDTKVP FCLQSCVKPL KYAIAVNDLG TEYVHRYVGK EPSGLRFNKL FLNEDDKPHN PMVNAGAIVV TSLIKQGVNN AEKFDYVMQF LNKMAGNEYV GFSNATFQSE RESGDRNFAI GYYLKEKKCF PEGTDMVGIL DFYFQLCSIE VTCESASVMA ATLANGGFCP ITGERVLSPE AVRNTLSLMH SCGMYDFSGQ FAFHVGLPAK SGVAGGILLV VPNVMGMMCW SPPLDKMGNS VKGIHFCHDL VSLCNFHNYD NLRHFAKKLD PRREGGDQRV KSVINLLFAA YTGDVSALRR FALSAMDMEQ RDYDSRTALH VAAAEGHVEV VKFLLEACKV NPFPKDRWNN TPMDEALHFG HHDVFKILQE YQVQYTPQGD SDDGKENQTV HKNLDGLL. It is sometimes possible for the material contained within the vial of "Glutaminase kidney isoform, mitochondrial, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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