Zinc finger protein GLIS3 (Glis3) Recombinant Protein | Glis3 recombinant protein
Recombinant Mouse Zinc finger protein GLIS3 (Glis3)
Gene Names
Glis3; 4833409N03Rik; E330013K21Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Zinc finger protein GLIS3 (Glis3); Recombinant Mouse Zinc finger protein GLIS3 (Glis3); Glis3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-780, Full length protein
Sequence
MMVQRLGPISPPASQVSTACKQISPSLPRAVNAANLNRPPSDTRSVILQESLVSTTLSLTESQSALSVKQEWSQSYRAFPSLSSSHSSQNGTDLGDLLSLPPGTPVSGNSVSNSLPPYLFGMENSHSPYPSPRHSATRAHSTRSKKRALSLSPLSDGIGIDFNTIIRTSPTSLVAYINGPRASPANLSPQSEVYGHFLGVRGSCIPQSCAVASGQKGILVASGGHTLPGYGEDGTLEYERMQQLEHGGLQPGPVNNMVLQPGLPGQDGQTANMLKTERLEEFPASALDLPSALPLPLPPPQGPPPPYHAHPHLHHPELLPHTQSLSLAQTGLEEDGEMEDSGGKHCCRWIDCSALYDQQEELVRHIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSREQQARKKLRSSTELHPDLLTDCLAVQPLQPATSPGDAADHTVGHSPGPGPGPGPGAELYSAPIFASNHSTRSGTAAGAGPPPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPPTPSPHHISPGRVPAPPSLLQRAQAPHSQQPPGSLLKPYQPETNSSFQPNGIHVHGFYGQLQTFCPPHYPDSQRTVPPSGSCSMVPSFEDCLVPTSMGQAGFDVFHRAFSTHSGITVYDLPSASSSLFGESLRSGPEDPTFLQLSAVDRCPSQLSSVYTEG
Sequence Length
780
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Glis3 recombinant protein
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein with five C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
72,374 Da
NCBI Official Full Name
zinc finger protein GLIS3 isoform X2
NCBI Official Synonym Full Names
GLIS family zinc finger 3
NCBI Official Symbol
Glis3
NCBI Official Synonym Symbols
4833409N03Rik; E330013K21Rik
NCBI Protein Information
zinc finger protein GLIS3
UniProt Protein Name
Zinc finger protein GLIS3
Protein Family
UniProt Gene Name
Glis3
NCBI Description
This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein which contains multiple C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the transcriptional regulation of insulin. It is thought to enhance GLI-RE-dependent transcription by binding to the GLI-RE consensus sequence (GACCACCCAC). Mutations in a similar gene in human have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Uniprot Description
Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3'.
Research Articles on Glis3
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Product Notes
The Glis3 glis3 (Catalog #AAA1425899) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-780, Full length protein. The amino acid sequence is listed below: MMVQRLGPIS PPASQVSTAC KQISPSLPRA VNAANLNRPP SDTRSVILQE SLVSTTLSLT ESQSALSVKQ EWSQSYRAFP SLSSSHSSQN GTDLGDLLSL PPGTPVSGNS VSNSLPPYLF GMENSHSPYP SPRHSATRAH STRSKKRALS LSPLSDGIGI DFNTIIRTSP TSLVAYINGP RASPANLSPQ SEVYGHFLGV RGSCIPQSCA VASGQKGILV ASGGHTLPGY GEDGTLEYER MQQLEHGGLQ PGPVNNMVLQ PGLPGQDGQT ANMLKTERLE EFPASALDLP SALPLPLPPP QGPPPPYHAH PHLHHPELLP HTQSLSLAQT GLEEDGEMED SGGKHCCRWI DCSALYDQQE ELVRHIEKVH IDQRKGEDFT CFWTGCPRRY KPFNARYKLL IHMRVHSGEK PNKCTFEGCK KAFSRLENLK IHLRSHTGEK PYLCQHPGCQ KAFSNSSDRA KHQRTHLDTK PYACQIPGCT KRYTDPSSLR KHVKAHSSRE QQARKKLRSS TELHPDLLTD CLAVQPLQPA TSPGDAADHT VGHSPGPGPG PGPGAELYSA PIFASNHSTR SGTAAGAGPP PHPVSHPSPG HNVQGSPHNP SSQLPPLTAV DAGAERFAPP TPSPHHISPG RVPAPPSLLQ RAQAPHSQQP PGSLLKPYQP ETNSSFQPNG IHVHGFYGQL QTFCPPHYPD SQRTVPPSGS CSMVPSFEDC LVPTSMGQAG FDVFHRAFST HSGITVYDLP SASSSLFGES LRSGPEDPTF LQLSAVDRCP SQLSSVYTEG. It is sometimes possible for the material contained within the vial of "Zinc finger protein GLIS3 (Glis3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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