Envelope glycoprotein I (GI) Recombinant Protein | GI recombinant protein
Recombinant Equine herpesvirus 1 Envelope glycoprotein I (GI)
NCBI and Uniprot Product Information
Uniprot Description
Function: In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips.
Subunit structure: Interacts with gE
By similarity.
Subcellular location: Virion membrane; Single-pass membrane protein
By similarity. Host cell membrane; Single-pass type I membrane protein
Potential. Host cell junction
By similarity. Host Golgi apparatus membrane; Single-pass type I membrane protein
By similarity. Note: During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN). The heterodimer gE/gI then redistribute to cell junctions to promote cell-cell spread later in the infection
By similarity.
Sequence similarities: Belongs to the alphaherpesvirinae glycoprotein I family.
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Product Notes
The Envelope glycoprotein I (GI) gi (Catalog #AAA1158050) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 23-424. The amino acid sequence is listed below: IIYRGEHMSM YLNASSEFAV YPTDQSLVLV GHLLFLDGQR LPTTNYSGLI ELIHYNYSSV CYTVIQTISY ESCPRVANNA FRSCLHKTSK HYHDYFRVNA SVETNVLLNI TKPQPTDSGA YILRVKLDHA PTADVFGVSA FVYDLKSKTV PDPMPTTQTV EPTTSYVSTP TYDYTDDVTT ETESTSTSTQ QAMTSTQTPS ATWGTQLTTE LPTNETVVIG QEALLCHWFQ PSTRVPTLYL HLLGRTGNLP EDVLLVEDSE FLRTTSPAHR PSASPADGDD FKQTNSTSLK ARNKIVAMVV IPTACVLMLL LVVVGAIING AVRKHLLSCA SRRIYRSGQG GASAAERRRL TCGPTLAASS ESLADDTTSS PPTPKPSKKT KLETDPLMEQ LNRKLEAIKE ES. It is sometimes possible for the material contained within the vial of "Envelope glycoprotein I (GI), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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