Growth hormone secretagogue receptor type 1 (Ghsr) Recombinant Protein | Ghsr recombinant protein
Recombinant Rat Growth hormone secretagogue receptor type 1 (Ghsr)
NCBI and Uniprot Product Information
NCBI Description
has G-protein coupled receptor binding activity to ligand ghrelin; plays a role in regulation of growth hormone release [RGD, Feb 2006]
Uniprot Description
GHSR: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). Defects in GHSR may be a cause of idiopathic short stature autosomal (ISSA). Short stature is defined by a subnormal rate of growth. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Cellular Component: neuron projection; cell surface; cell; integral to membrane; plasma membrane; lipid raft
Molecular Function: growth hormone secretagogue receptor activity; G-protein coupled receptor activity; protein binding; growth hormone receptor binding; hormone binding; peptide hormone binding; growth hormone-releasing hormone receptor activity
Biological Process: response to food; positive regulation of insulin-like growth factor receptor signaling pathway; hormone-mediated signaling; response to hormone stimulus; adult feeding behavior; negative regulation of interleukin-6 biosynthetic process; decidualization; positive regulation of multicellular organism growth; negative regulation of interleukin-1 beta production; negative regulation of insulin secretion; G-protein coupled receptor protein signaling pathway; growth hormone secretion; positive regulation of fatty acid metabolic process; cellular response to insulin stimulus; regulation of synaptogenesis; negative regulation of inflammatory response; actin polymerization and/or depolymerization; positive regulation of appetite; regulation of hindgut contraction; negative regulation of tumor necrosis factor biosynthetic process
Research Articles on Ghsr
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Product Notes
The Ghsr ghsr (Catalog #AAA1242751) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-364. The amino acid sequence is listed below: MWNATPSEEP EPNVTLDLDW DASPGNDSLP DELLPLFPAP LLAGVTATCV ALFVVGISGN LLTMLVVSRF RELRTTTNLY LSSMAFSDLL IFLCMPLDLV RLWQYRPWNF GDLLCKLFQF VSESCTYATV LTITALSVER YFAICFPLRA KVVVTKGRVK LVILVIWAVA FCSAGPIFVL VGVEHENGTD PRDTNECRAT EFAVRSGLLT VMVWVSSVFF FLPVFCLTVL YSLIGRKLWR RRGDAAVGAS LRDQNHKQTV KMLAVVVFAF ILCWLPFHVG RYLFSKSFEP GSLEIAQISQ YCNLVSFVLF YLSAAINPIL YNIMSKKYRV AVFKLLGFES FSQRKLSTLK DESSRAWTKS SINT. It is sometimes possible for the material contained within the vial of "Growth hormone secretagogue receptor type 1 (Ghsr), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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