Golgi to ER traffic protein 4 homolog (get4) Recombinant Protein | get4 recombinant protein
Recombinant Salmo salar Golgi to ER traffic protein 4 homolog (get4)
NCBI and Uniprot Product Information
Uniprot Description
As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
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Product Notes
The get4 get4 (Catalog #AAA1241410) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-322, Full length protein. The amino acid sequence is listed below: MSEQEALKCS SARNRGGTQR VEGKLRASVE KGDYYEAHQM YRTLFFRYIS QAKHTDAREL MYNGAQLFFS YNQLNSAADL SMLVLESLEK SEAKVEDEDL EHLAKLFSLM DPNSPERVAF VSRALKWSTG GSGKLGAPKL HQLLAVTLWK EQNYSESRYH FLHSSDGEGC AQMLVEYSAQ RGFRSEVDMF VAQAVLQFLC LKNKNSASVV FSTYTQKHPS IEKDPPFVQP LLNFIWFLLL AVDGGKLTVF TVLCEQYQPS LKRDPMYNEY LDRIGQLFFG VPPKQSSSYG GLLGNLLNSL MGSGEDEEGE EAQEHGSPIE LD. It is sometimes possible for the material contained within the vial of "Golgi to ER traffic protein 4 homolog (get4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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