ATPase GET3 (GET3) Recombinant Protein | GET3 recombinant protein
Recombinant Scheffersomyces stipitis ATPase GET3 (GET3)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
ATPase GET3 (GET3); Recombinant Scheffersomyces stipitis ATPase GET3 (GET3); ATPase GET3; EC=3.6.-.-; Arsenical pump-driving ATPase; Arsenite-stimulated ATPase; Golgi to ER traffic protein 3; Guided entry of tail-anchored proteins 3; GET3 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-347aa; full length protein
Sequence
MDFELEPTLE SIVQQDTLKW IFVGGKGGVG KTTTSSSIAV QLALNHPNDQ FLLISTDPAHNLSDAFCQKF GKDARKVDGL SNLSCMEIDP EAAMSDLQQQ AQQYNNDPND PLKSMMNDMTGSIPGIDEAL SFMEVLKHIK SQKVDENDDK DKISYRTIIF DTAPTGHTLR FLQLPSTLQKLLSKFQALSG KFGPMMSMLG GGNQQEMFDK LNEVQKNVTE VNEQFTNPDL TTFVCVCISEFLSLYETERM IQELMSYNMD VNSIVVNQLL FADDDEKPCK RCVSRWKMQK KYLDQMAELYEDYHLVKMPL LGTEIRGVEN LKKFSKFLLT PYDPKVNGDL VTSLEEK
Sequence Length
347
Species
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,294 Da
NCBI Official Full Name
pump-driving ATPase
NCBI Official Symbol
ARR4
NCBI Protein Information
pump-driving ATPase
UniProt Protein Name
ATPase GET3
Protein Family
UniProt Gene Name
GET3
UniProt Entry Name
GET3_PICST
Uniprot Description
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
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Product Notes
The GET3 get3 (Catalog #AAA1211905) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-347aa; full length protein. The amino acid sequence is listed below: MDFELEPTLE SIVQQDTLKW IFVGGKGGVG KTTTSSSIAV QLALNHPNDQ FLLISTDPAH NLSDAFCQKF GKDARKVDGL SNLSCMEIDP EAAMSDLQQQ AQQYNNDPND PLKSMMNDMT GSIPGIDEAL SFMEVLKHIK SQKVDENDDK DKISYRTIIF DTAPTGHTLR FLQLPSTLQK LLSKFQALSG KFGPMMSMLG GGNQQEMFDK LNEVQKNVTE VNEQFTNPDL TTFVCVCISE FLSLYETERM IQELMSYNMD VNSIVVNQLL FADDDEKPCK RCVSRWKMQK KYLDQMAELY EDYHLVKMPL LGTEIRGVEN LKKFSKFLLT PYDPKVNGDL VTSLEEK. It is sometimes possible for the material contained within the vial of "ATPase GET3 (GET3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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