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Typical Testing Data/Standard Curve (for reference only)

General Mycophenolic Acid ELISA Kit

Mycophenolic Acid ELISA Kit

Reactivity
General
Synonyms
Mycophenolic Acid; Mycophenolic Acid ELISA Kit; Mycophenolic Acid elisa kit
Ordering
For Research Use Only!
Reactivity
General
Specificity
A Competitive ELISA Kit for the quantification of MPA in serum; urine and other biological samples.
Assay Type
Competitive
Detection Method
Absorbance (450nM)
Sample Type
Serum, Other biological fluids, Urine
Detection Range
1-256ng/ml
Sensitivity
0.5ng/ml
Preparation and Storage
Store at -20 degree C
Shipping: Gel Pack
Shelf Life: Est.~12 months

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for Mycophenolic Acid elisa kit
Mycophenolic acid (MPA), also known as mycophenolate, is produced by a mold species called Penicillium brevicompactum and is an immunosuppressive agent used to prevent rejection following kidney, heart, and liver transplants. The mechanism of action of MPA is to directly bind to inosine-5?-monophosphate dehydrogenase (IMPDH) which is an enzyme essential for the de novo synthesis of guanosine-5'-monophosphate from inosine-5'-monophosphate. MPA is a potent, reversible, non-competitive inhibitor of IMPDH and it can specifically inhibit proliferative responses of T- and B-lymphocytes by blocking the de novo pathway of guanosine nucleotide synthesis. MPA can be also used in treating different autoimmune diseases and similar immune-mediated disorders including Crohn's disease, Behçet's disease, pemphigus vulgaris, small vessel vasculitides, rheumatoid arthritis and psoriasis. There are some common side effects such as nausea, diarrhea, anemia, gastrointestinal bleeding and infections and therefore it is important to monitor MPA levels in the body. The traditional techniques/instruments (HPLC or GC-MS) for detecting MPA are expensive, laborious, and time-consuming. On the other hand, immunoassay techniques, such as ELISA, are commonly preferred as simple, reliable and rapid methods. MPA ELISA kit is a competitive-based ELISA that can detect MPA in different biological samples such as serum and urine. It can detect MPA (1-256ng/ml) within 90 minutes (LOD 0.5ng/ml).

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Product Notes

The General Mycophenolic Acid (Catalog #AAA8400534) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8400534 ELISA Kit recognizes General Mycophenolic Acid. It is sometimes possible for the material contained within the vial of "Mycophenolic Acid, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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