ATPase ASNA1 homolog (GE23838) Recombinant Protein | GE23838 recombinant protein

Recombinant Drosophila yakuba ATPase ASNA1 homolog (GE23838)

Cat. Num. AAA1117765

• Gene Names: DyakGE23838; DyakCG1598; dyak_GLEANR_759; GE23838
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: ATPase ASNA1 homolog (GE23838); Recombinant Drosophila yakuba ATPase ASNA1 homolog (GE23838); GE23838 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-336, full length protein
• Sequence: MVDNLEPLEPSLQNLVEQDSLKWIFVGGKGGVGKTTCSSSLAVQLSKVRESVLIISTDPAHNISDAFDQKFTKVPTKVNGFDNLFAMEIDPNAGLNELPEEYFEGENEALRVSKGVMQEMINALPGIDEAMSYAEVMKLVKGMNFSVVVFDTAPTGHTLRLIAFPQVVEKGLGKLLRLKMKVAPLLSQFVSMLGMADLNADTLSQKLDDMLRVITQVNEQFKNPDQTTFVCVCIAEFFSLYETERLVQELTKCGIDVHNIIVNQLLFLQNSHDSCSMCASRFKIQEKYLDQIADLYEDFHVTKLPLLEKEVRGPESIRSFSENLMKPYEPKAKPKE
• Sequence Length: 336

• Species: Drosophila yakuba (Fruit fly)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 195474422
• NCBI GeneID: 6528444
• NCBI Accession #: XP_002089490.1
• NCBI GenBank Nucleotide #: XM_002089454.2
• UniProt Accession #: B4P1R6
• Molecular Weight: 37,665 Da
• NCBI Official Full Name: uncharacterized protein Dyak_GE23838
• NCBI Official Symbol: DyakGE23838
• NCBI Official Synonym Symbols: DyakCG1598; dyak_GLEANR_759; GE23838
• NCBI Protein Information: GE23838 gene product from transcript GE23838-RA
• UniProt Protein Name: ATPase ASNA1 homolog
• UniProt Gene Name: GE23838

Uniprot Description

ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.