Herpes Simplex Virus-1 gD Recombinant Protein | HSV-1 gD recombinant protein
Herpes Simplex Virus-1 gD Recombinant
Recombinant HSV1 gD contains an N terminal GST purification tag and migrates as an approximately 42 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE.
Upon reconstitution, this protein can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
NCBI and Uniprot Product Information
Uniprot Description
Function: Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM, PVRL1 and 3-O-sulfated heparan sulfate. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL
By similarity.
Subunit structure: Homodimer
By similarity. Interacts with host receptor TNFRSF14. Interacts with host receptor PVRL1. Interacts (via profusion domain) with gB; this interaction occurs in the absence of gH/gL. Interacts (via profusion domain) with gH/gL heterodimer; this interaction occurs in the absence of gB. Associates with the gB-gH/gL-gD complex. Interacts (via C-terminus) with UL11 tegument protein
By similarity.
Subcellular location: Virion membrane; Single-pass type I membrane protein
By similarity. Note: During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs
By similarity.
Sequence similarities: Belongs to the herpesviridae glycoprotein D family.
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Product Notes
The HSV-1 gD gd (Catalog #AAA553221) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Recombinant human Herpesvirus-1 gD antigen is suitable for ELISA and Western blots, excellent antigen for detection of HSV with minimal specificity problems. . Researchers should empirically determine the suitability of the HSV-1 gD gd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Herpes Simplex Virus-1 gD, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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