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Glutamate Decarboxylase 2 Recombinant Protein | GAD2 recombinant protein

Recombinant Human Glutamate Decarboxylase 2

Gene Names
GAD2; GAD65
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Glutamate Decarboxylase 2; Recombinant Human Glutamate Decarboxylase 2; GAD2 Human; Glutamate Decarboxylase 2 Human Recombinant; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain; 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 65 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65; GAD65; 65kD); Glutamate Decarboxylase-2 (Pancreas); EC 4.1.1; GAD2; GAD2 recombinant protein
Ordering
For Research Use Only!
Host
Sf9 Insect Cells
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
GAD2 protein solution is supplied in 16mM HEPES buffer pH-7.5, 250mM NaCl, 0.016mM Pyridoxal-5’-Phosphate, 0.16% Triton x-100 and 20% glycerol.
Sequence Length
585
Physical Appearance
Sterile Filtered clear solution.
Immunological Functions
1. Binds IgG type human auto-antibodies.
2. Standard ELISA test (checker-board analysis of positive/negative sera panels).
Preparation and Storage
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.
Related Product Information for GAD2 recombinant protein
Recombinant Human GAD2 produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 64 kDa.
GAD2 is expressed with a 6xHis tag at N-terminus and purified by proprietary chromatographic techniques.
Product Categories/Family for GAD2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
glutamate decarboxylase 2
NCBI Official Synonym Full Names
glutamate decarboxylase 2
NCBI Official Symbol
GAD2
NCBI Official Synonym Symbols
GAD65
NCBI Protein Information
glutamate decarboxylase 2
UniProt Protein Name
Glutamate decarboxylase 2
Protein Family
UniProt Gene Name
GAD2
UniProt Synonym Gene Names
GAD65; GAD-65
UniProt Entry Name
DCE2_HUMAN

Uniprot Description

GAD2: Catalyzes the production of GABA. Homodimer. Belongs to the group II decarboxylase family.

Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; Carbohydrate Metabolism - butanoate; EC 4.1.1.15; Lyase; Other Amino Acids Metabolism - beta-alanine; Other Amino Acids Metabolism - taurine and hypotaurine

Chromosomal Location of Human Ortholog: 10p11.23

Cellular Component: plasma membrane

Molecular Function: glutamate decarboxylase activity; protein binding

Biological Process: neurotransmitter secretion; synaptic transmission

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Product Notes

The GAD2 gad2 (Catalog #AAA140948) is a Recombinant Protein produced from Sf9 Insect Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Glutamate Decarboxylase 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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