F2 Blocking Peptide | FRAT2 blocking peptide

FRAT2 Antibody (C-term) Blocking peptide

• Synonyms: F2; FRAT2 Antibody (C-term) Blocking peptide; GSK-3-binding protein FRAT2; Frequently rearranged in advanced T-cell lymphomas 2; FRAT-2; FRAT2; FRAT2 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 233

• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for FRAT2 blocking peptide

Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.

NCBI and Uniprot Product Information

• NCBI GI #: 92058701
• NCBI GeneID: 23401
• UniProt Accession #: O75474; Q5JTI0; Q8WUL9; Q9BYG2
• Molecular Weight: 24,051 Da
• NCBI Official Full Name: GSK-3-binding protein FRAT2
• NCBI Official Synonym Full Names: frequently rearranged in advanced T-cell lymphomas 2
• NCBI Official Symbol: FRAT2
• NCBI Protein Information: GSK-3-binding protein FRAT2
• UniProt Protein Name: GSK-3-binding protein FRAT2
• Protein Family: GSK-3-binding protein
• UniProt Gene Name: FRAT2
• UniProt Synonym Gene Names: FRAT-2
• UniProt Entry Name: FRAT2_HUMAN

NCBI Description

The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression. [provided by RefSeq, Jul 2008]

Uniprot Description

FRAT2: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. Belongs to the GSK-3-binding protein family.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 10q24.1

Cellular Component: cytosol