Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA) Recombinant Protein | FNTA recombinant protein
Recombinant Bovine Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA); Recombinant Bovine Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA); FNTA recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-375, Full length protein
Sequence
AAADGVGEAAQGGDPGQPEPPPPPQPHPPPPPPQPPQEEAAAASPIDDGFLSLDSPTYVLYRDRPEWADIDPVPQNDGPNPVVQIIYSEKFQDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYISAIIEEQPKNYQVWHHRRVLVEWLRDPSQELEFIADILTQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVISNTTGYNDRAILEREVQYTLEMIKLVPHNESAWNYLKGILQDRGLSKYPNLLNQLLDLQPSHSSPYLIAFLVDIYEDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKHSTESDPPTNVQQ
Sequence Length
374
Species
Bovine
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for FNTA recombinant protein
Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein s with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,845 Da
NCBI Official Full Name
protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
NCBI Official Synonym Full Names
farnesyltransferase, CAAX box, alpha
NCBI Official Symbol
FNTA
NCBI Protein Information
protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
UniProt Protein Name
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Protein Family
UniProt Gene Name
FNTA
UniProt Synonym Gene Names
GGTase-I-alpha
Uniprot Description
Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation ().
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Product Notes
The FNTA fnta (Catalog #AAA965799) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-375, Full length protein. The amino acid sequence is listed below: AAADGVGEAA QGGDPGQPEP PPPPQPHPPP PPPQPPQEEA AAASPIDDGF LSLDSPTYVL YRDRPEWADI DPVPQNDGPN PVVQIIYSEK FQDVYDYFRA VLQRDERSER AFKLTRDAIE LNAANYTVWH FRRVLLKSLQ KDLHEEMNYI SAIIEEQPKN YQVWHHRRVL VEWLRDPSQE LEFIADILTQ DAKNYHAWQH RQWVIQEFKL WDNELQYVDQ LLKEDVRNNS VWNQRYFVIS NTTGYNDRAI LEREVQYTLE MIKLVPHNES AWNYLKGILQ DRGLSKYPNL LNQLLDLQPS HSSPYLIAFL VDIYEDMLEN QCDNKEDILN KALELCEILA KEKDTIRKEY WRYIGRSLQS KHSTESDPPT NVQQ. It is sometimes possible for the material contained within the vial of "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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