Human Flt-3ligand ELISA Kit | FLT3LG elisa kit

Human Flt-3ligand PicoKine ELISA Kit

Cat. Num. AAA177359

• Gene Names: FLT3LG; FL; FLT3L
• Reactivity: Human
• Synonyms: Flt-3ligand; Human Flt-3ligand PicoKine ELISA Kit; Fms-related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; Flt 3L; Flt3 L; FLT3 LG; Flt3L; FLT3LG; Fms related tyrosine kinase 3 ligand; SL cytokine; FLT3LG elisa kit

• Reactivity: Human
• Sequence Length: 235

• Samples: feces.
• Preparation and Storage: Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)

Typical Testing Data/Standard Curve (for reference only)

(Human Flt-3ligand PicoKine ELISA Kit standard curve )

Related Product Information for FLT3LG elisa kit

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rotavirus antigen. Standards or samples are then added to the appropriate microtiter plate wells with a HRP-conjugated antibody preparation specific for Rotavirus antigen to each microplate well and incubated. Then a TMB (3,3',5,5' tetramethyl-benzidine) substrate solution is added to each well. Only those wells that contain Rotavirus antigen, HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of Rotavirus antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 1706818
• NCBI GeneID: 2323
• UniProt Accession #: P49771; Q05C96; A0AVC2; B9EGH2
• Molecular Weight: 17,290 Da
• NCBI Official Full Name: Fms-related tyrosine kinase 3 ligand
• NCBI Official Synonym Full Names: fms-related tyrosine kinase 3 ligand
• NCBI Official Symbol: FLT3LG
• NCBI Official Synonym Symbols: FL; FLT3L
• NCBI Protein Information: fms-related tyrosine kinase 3 ligand; flt3 ligand
• UniProt Protein Name: Fms-related tyrosine kinase 3 ligand
• Protein Family: Fms-related tyrosine kinase
• UniProt Gene Name: FLT3LG
• UniProt Synonym Gene Names: Flt3 ligand; Flt3L
• UniProt Entry Name: FLT3L_HUMAN

NCBI Description

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

Uniprot Description

FLT3LG: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cytokine; Ligand, receptor tyrosine kinase

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: extracellular space; membrane; integral to membrane

Molecular Function: protein homodimerization activity; cytokine activity; receptor tyrosine kinase binding; receptor binding

Biological Process: regulation of myeloid dendritic cell activation; positive regulation of natural killer cell differentiation; lymphocyte differentiation; embryonic hemopoiesis; positive regulation of cell proliferation; positive regulation of protein amino acid phosphorylation; signal transduction; positive regulation of myoblast differentiation