SDS-PAGE
Peptidyl-prolyl cis-trans isomerase FKBP3 Recombinant Protein | FKBP3 recombinant protein
Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP3
SDS-PAGE
SDS-PAGE
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]
Uniprot Description
FKBP3: FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins. Belongs to the FKBP-type PPIase family.
Protein type: EC 5.2.1.8; Isomerase
Chromosomal Location of Human Ortholog: 14q21.2
Cellular Component: endoplasmic reticulum membrane; nucleus
Molecular Function: FK506 binding; peptidyl-prolyl cis-trans isomerase activity; protein binding; receptor activity
Biological Process: protein peptidyl-prolyl isomerization
Research Articles on FKBP3
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Product Notes
The FKBP3 fkbp3 (Catalog #AAA969523) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-224aa; Full Length. The amino acid sequence is listed below: AAAVPQRAWT VEQLRSEQLP KKDIIKFLQE HGSDSFLAEH KLLGNIKNVA KTANKDHLVT AYNHLFETKR FKGTESISKV SEQVKNVKLN EDKPKETKSE ETLDEGPPKY TKSVLKKGDK TNFPKKGDVV HCWYTGTLQD GTVFDTNIQT SAKKKKNAKP LSFKVGVGKV IRGWDEALLT MSKGEKARLE IEPEWAYGKK GQPDAKIPPN AKLTFEVELV DID. It is sometimes possible for the material contained within the vial of "Peptidyl-prolyl cis-trans isomerase FKBP3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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