Protein four-jointed (fj) Recombinant Protein | fj recombinant protein
Recombinant Drosophila melanogaster Protein four-jointed (fj), partial
NCBI and Uniprot Product Information
Uniprot Description
Golgi serine/threonine protein kinase required for intermediate growth in the proximal-distal axis. Phosphorylates specific residues within extracellular cadherin domains of Fat (ft) and Dachsous (ds) as they transit through the Golgi (PubMed:18635802). Acts in ommatidial polarity determination as a secondary signal downstream of Notch, JAK/STAT and wingless. Also necessary for the initiation, up-regulation or maintenance of Notch ligand, Serrate (Ser) expression in legs, thereby participating in a feedback loop with N signaling. Sufficient for joint formation and growth in the leg (PubMed:10607560, PubMed:11566858, PubMed:14757640, PubMed:7555705, PubMed:8606003).
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Product Notes
The fj fj (Catalog #AAA1030435) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 100-583. The amino acid sequence is listed below: G LPRHQDSPPD LPEEQIQMVA VEPLSSYRVE FIKETDELSA EQVFRNAFHL EQDKDAPDSM VVKKLDTNDG SIKEFHVQRT ASGRYRKGPE RRLSKKMPER VQPQETSRSP TTSPTNPTSE HQAGFIEEDV YWGPTVEQAL PKGFAAKDQV SWERFVGEQG RVVRLEQGCG RMQNRMVVFA DGTRACARYR QNTDQIQGEI FSYYLGQLLN ISNLAPSAAT VVDTSTPNWA AALGDITQAQ WKERRPVVLT RWLSDLEPAG IPQPFQPLER HLNKHDVWNL TRHMQSERQA QSQPHGLLKR LGAASSPGSA HQSNAIEETG TGTETANGAL VQRLIELAQW SDLIVFDYLI ANLDRVVNNL YNFQWNADIM AAPAHNLARQ SASQLLVFLD NESGLLHGYR LLKKYEAYHS LLLDNLCVFR RPTIDALRRL RAAGAGRRLR DLFERTTSAG VRDVLPSLPD KSVKILVERI DRVLGQVQKC QGS. It is sometimes possible for the material contained within the vial of "Protein four-jointed (fj), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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