SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
FGF-21 recombinant protein
Recombinant FGF-21
Applications
SDS-Page
Purity
>95% by SDS-PAGE
Synonyms
FGF-21; Recombinant FGF-21; FGF 21; Fgf21; FGF21_HUMAN; FGFL; Fibroblast growth factor 21; PRO10196; UNQ3115; FGF-21 recombinant protein
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; In Phosphate Buffered Saline (pH 7.4) containing 10% Glycerol
Concentration
0.5mg/ml (Determined by Absorbance at 280nm) (varies by lot)
Sequence Positions
29-210aa
Sequence
MGSSHHHHHH SSGLVPRGSF MSGM AYPIPD SSPLLQFGGQ VRQRYLYTDD DQDTEAHLEI REDGTVVGAA HRSPESLLEL KALKPGVIQI LGVKASRFLC QQPDGALYGS PHFDPEACSF RELLLEDGYN VYQSEAHGLP LRLPQKDSPN QDATSWGPVR FLPMPGLLHE PQDQAGFLPP EPPDVGSSDP LSMVEPLQGR SPSYAS
Sequence Length
210
Applicable Applications for FGF-21 recombinant protein
SDS-PAGE
Species
Mouse
Endotoxin
< 1 EU per 1ug of protein (Determined by LAL method)
Tag
His-Tag
Preparation and Storage
Can be stored at 2 degree C to 8 degree C for 1 week. For long term storage, aliquot and store at -20 degree C to -80 degree C. Avoid repeated freezing and thawing cycles.
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
SDS-Page
(3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain)
Related Product Information for FGF-21 recombinant protein
FGF-21, also known as fibroblast growth factor 21, is a member of the fibroblast growth factor family. It has a hydrophobic amino terminus, which is a typical signal sequence, and appears to be a secreted protein. It stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression. Recombinant mouse FGF-21, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Product Categories/Family for FGF-21 recombinant protein
References
Kharitonenkov A., et al. (2005) J Clin Invest. 115:1627-1635. Yamauchi H., et al. (2006) EMBO Rep. 7:649-654.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22.5 kDa (206aa), Confirmed by MALDI-TOF
NCBI Official Full Name
fibroblast growth factor 21
NCBI Official Synonym Full Names
fibroblast growth factor 21
NCBI Official Symbol
Fgf21
NCBI Protein Information
fibroblast growth factor 21
UniProt Protein Name
Fibroblast growth factor 21
UniProt Gene Name
Fgf21
UniProt Synonym Gene Names
FGF-21
UniProt Entry Name
FGF21_MOUSE
Uniprot Description
FGF21: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Belongs to the heparin-binding growth factors family.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular space
Biological Process: positive regulation of cell proliferation; positive regulation of glucose import
Research Articles on FGF-21
Similar Products
Product Notes
The FGF-21 fgf21 (Catalog #AAA201162) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-210aa. AAA Biotech's FGF-21 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the FGF-21 fgf21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MGSSHHHHHH SSGLVPRGSF MSGM AYPIPD SSPLLQFGGQ VRQRYLYTDD DQDTEAHLEI REDGTVVGAA HRSPESLLEL KALKPGVIQI LGVKASRFLC QQPDGALYGS PHFDPEACSF RELLLEDGYN VYQSEAHGLP LRLPQKDSPN QDATSWGPVR FLPMPGLLHE PQDQAGFLPP EPPDVGSSDP LSMVEPLQGR SPSYAS. It is sometimes possible for the material contained within the vial of "FGF-21, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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