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Human IgG receptor FcRn large subunit p51 ELISA Kit | FCGRT elisa kit

Human IgG receptor FcRn large subunit p51 ELISA Kit

Gene Names
FCGRT; FCRN; alpha-chain
Reactivity
Human
Synonyms
IgG receptor FcRn large subunit p51; Human IgG receptor FcRn large subunit p51 ELISA Kit; FcRn; IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor; FCGRT; FCRN; FCGRT elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Samples
Serum, plasma, tissue homogenates and other biological fluids.
Detection Range
0.312-20 ng/mL
Sensitivity
Less than 0.098ng/mL
Assay Time
3-5h
Sample Volume
100T
Detection Wavelength
450 nm
Preparation and Storage
Store at 4 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,743 Da
NCBI Official Full Name
IgG receptor FcRn large subunit p51
NCBI Official Synonym Full Names
Fc fragment of IgG receptor and transporter
NCBI Official Symbol
FCGRT
NCBI Official Synonym Symbols
FCRN; alpha-chain
NCBI Protein Information
IgG receptor FcRn large subunit p51
UniProt Protein Name
IgG receptor FcRn large subunit p51
Protein Family
UniProt Gene Name
FCGRT
UniProt Synonym Gene Names
FCRN; FcRn

NCBI Description

This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Uniprot Description

FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: plasma membrane

Molecular Function: beta-2-microglobulin binding; IgG binding; IgG receptor activity; peptide antigen binding

Research Articles on FCGRT

Similar Products

Product Notes

The Human FCGRT fcgrt (Catalog #AAA9427126) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9427126 ELISA Kit recognizes Human FCGRT. It is sometimes possible for the material contained within the vial of "IgG receptor FcRn large subunit p51, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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