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High affinity immunoglobulin epsilon receptor subunit alpha Recombinant Protein | Fcer1a recombinant protein
High affinity immunoglobulin epsilon receptor subunit alpha
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
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NCBI and Uniprot Product Information
Uniprot Description
FCER1A: Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Protein type: Membrane protein, integral
Cellular Component: cell surface; external side of plasma membrane; integral to plasma membrane; lipid raft
Molecular Function: IgE binding; IgE receptor activity; protein binding
Biological Process: activation of JNK activity; activation of MAPK activity; cell surface receptor linked signal transduction; leukotriene biosynthetic process; positive regulation of calcium-mediated signaling; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of interleukin-3 biosynthetic process; positive regulation of mast cell degranulation; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of type I hypersensitivity; serotonin secretion; signal transduction
Research Articles on Fcer1a
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Product Notes
The Fcer1a fcer1a (Catalog #AAA7042726) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 24-250aa; Full Length of Mature Protein. The amino acid sequence is listed below: ATEKSVLTLD PPWIRIFTGE KVTLSCYGNN HLQMNSTTKW IHNGTVSEVN SSHLVIVSAT VQDSGKYICQ KQGLFKSKPV YLNVTQDWLL LQTSADMVLV HGSFDIRCHG WKNWNVRKVI YYRNDHAFNY SYESPVSIRE ATLNDSGTYH CKGYLRQVKY ESDKFRIAVV KAYKCKYYWL QLIFPLLVAI LFAVDTGLLL STEEQFKSVL EIQKTGKYKK VETELLT . It is sometimes possible for the material contained within the vial of "High affinity immunoglobulin epsilon receptor subunit alpha, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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