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FBLN2 / Fibulin-2 Recombinant Protein | FBLN2 recombinant protein

Human FBLN2 / Fibulin-2 Recombinant Protein

Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
FBLN2 / Fibulin-2; Human FBLN2 / Fibulin-2 Recombinant Protein; Fibulin-2; FIBL-2; FBLN2 recombinant protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
1231
Applicable Applications for FBLN2 recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Homotrimer; disulfide-linked. Interacts with LAMA2 (By similarity). Interacts with FBN1 (via N-terminal domain). Forms a ternary complex with ELN and FBN1 (PubMed:17255108).
Entry Function
Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
fibulin-2 isoform a
NCBI Official Synonym Full Names
fibulin 2
NCBI Official Symbol
FBLN2
NCBI Protein Information
fibulin-2
UniProt Protein Name
Fibulin-2
Protein Family
UniProt Gene Name
FBLN2
UniProt Synonym Gene Names
FIBL-2
UniProt Entry Name
FBLN2_HUMAN

NCBI Description

This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

FBLN2: Its binding to fibronectin and some other ligands is calcium dependent. Belongs to the fibulin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular region; vesicle

Molecular Function: extracellular matrix binding; extracellular matrix structural constituent; calcium ion binding

Biological Process: extracellular matrix organization and biogenesis

Research Articles on FBLN2

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Product Notes

The FBLN2 fbln2 (Catalog #AAA2901586) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FBLN2 / Fibulin-2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the FBLN2 fbln2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FBLN2 / Fibulin-2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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