Human family with sequence similarity 21, member C ELISA Kit | FAM21C elisa kit
Human WASH complex subunit FAM21C, FAM21C ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
FAM21C: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes. Plays a role in fluid-phase endocytosis, a process exploited by vaccinia intracellular mature virus (IMV) to enter cells. As a result, may facilitate the penetration of IMV into cells. Belongs to the FAM21 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 10q11.1
Cellular Component: early endosome membrane; early endosome; plasma membrane; endosome
Molecular Function: protein binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-5-phosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol 3-phosphate binding
Biological Process: protein transport; retrograde transport, endosome to Golgi
Research Articles on FAM21C
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Product Notes
The Human FAM21C fam21c (Catalog #AAA9317421) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9317421 ELISA Kit recognizes Human FAM21C. It is sometimes possible for the material contained within the vial of "family with sequence similarity 21, member C, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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