Western Blot (WB)
(Western Blot analysis of FAM21C expression in transfected 293T cell line by FAM21C polyclonal antibody. Lane 1: FAM21C transfected lysate (31.13kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human FAM21C Polyclonal Antibody | anti-FAM21C antibody
FAM21C (WASH Complex Subunit FAM21C, Vaccinia Virus Penetration Factor, VPEF, KIAA0592)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of FAM21C expression in transfected 293T cell line by FAM21C polyclonal antibody. Lane 1: FAM21C transfected lysate (31.13kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of FAM21C expression in transfected 293T cell line by FAM21C polyclonal antibody. Lane 1: FAM21C transfected lysate (31.13kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
Uniprot Description
FAM21C: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes. Plays a role in fluid-phase endocytosis, a process exploited by vaccinia intracellular mature virus (IMV) to enter cells. As a result, may facilitate the penetration of IMV into cells. Belongs to the FAM21 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 10q11.1
Cellular Component: early endosome membrane; early endosome; plasma membrane; endosome
Molecular Function: phosphatidylinositol-4,5-bisphosphate binding; protein binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-5-phosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol 3-phosphate binding
Biological Process: protein transport; retrograde transport, endosome to Golgi
Research Articles on FAM21C
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Product Notes
The FAM21C fam21c (Catalog #AAA6011596) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FAM21C (WASH Complex Subunit FAM21C, Vaccinia Virus Penetration Factor, VPEF, KIAA0592) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FAM21C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the FAM21C fam21c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MSVPRGPIAQ WADGAISPNG HRPQLRAASG EDSTEEALAA AAAPWEGGPV PGVDTSPFAK SLGHSRGEAD LFDSGDIFST GTGSQSVERT KPKAKIAENP ANPPVGGKAK SPMFPALGEA SSDDDLFQSA KPKPAKKTNP FPLLEDEDDL FTDQKVKKNE TKSSSQQDVI LTTQDIFEDD IFATEAIKPS QKTREKEKTL ESNLFDDNID IFADLTVKPK EKSKKKVEAK SIFDDDMDDI FSTGIQAKTT KPKSRSAQAA PEPRFEHKVS NIFDDPLNAF GGQ. It is sometimes possible for the material contained within the vial of "FAM21C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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