Redox-regulatory protein FAM213A (fam213a) Recombinant Protein | fam213a recombinant protein
Recombinant Danio rerio Redox-regulatory protein FAM213A (fam213a)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to a subfamily of FAM213A/selenoprotein U (SelU), within a peroxiredoxin-like FAM213 superfamily. SelU is unusual in that it has restricted phylogenetic distribution in vertebrates, such as in chicken and fish. Other vertebrate members of this family, including mammals, contain cysteine-containing homologues. SelU proteins contain UxxC (U for selenocysteine and C for cysteine) motif in place of the catalytic CxxC motif found in cysteine-containing homologues. The latter function as redox regulatory proteins, suggesting a similar role for SelU proteins. Like majority of selenoproteins, SelU contains a single selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs in vertebrates contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. A paralog of this gene exists on chromosome 12 (GeneID:767744). [provided by RefSeq, Aug 2017]
Uniprot Description
Involved in redox regulation of the cell. Acts as an antioxidant ().
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Product Notes
The fam213a fam213a (Catalog #AAA1402659) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-212, Full length protein. The amino acid sequence is listed below: MGMWSLGLGA VGAAIAGLIL ANTDFLLTKS APATVDYLAN ADLKTIDGDE RSLKAKALWE KSGAVIMAVR RPGUFLCREE ASELSSLKPQ LDELGVPLYA VVKENVGTEI QDFRPHFAGE IFLDEKQAFY GPQQRKMGGL GFIRLGVWQN FVRAWRAGYQ GNMNGEGFIL GGVFVMGSGG QGVLLEHREK EFGDKVSLES VLEAAKKVVV EK. It is sometimes possible for the material contained within the vial of "Redox-regulatory protein FAM213A (fam213a), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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