Extracellular serine/threonine protein kinase FAM20C (Fam20c) Recombinant Protein | Fam20c recombinant protein
Recombinant Mouse Extracellular serine/threonine protein kinase FAM20C (Fam20c)
Gene Names
Fam20c; DMP4; DMP-4; C76981; GEF-CK; mKIAA4081
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Extracellular serine/threonine protein kinase FAM20C (Fam20c); Recombinant Mouse Extracellular serine/threonine protein kinase FAM20C (Fam20c); Fam20c recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
88-579aa; Full Length of Mature Protein
Sequence
DFSSDPASNLTSHSLEKLPSAAEPVDHAPRGQEPRSPPPRDPAHRPLLRDPGPRPRVPPPGPSGDGSLLAKLFEHPLYQGAVPPLTEDDVLFNVNSDIRFNPKAAENPDWPHEGAEGAEFLPTGEAAVNLYPNWLKFHIGINRYELYSRHNPAIDALLRDLGSQKITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRMINMTKEIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGRPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGHRILDIMDMTVFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILAPLHQCCRIRRSTYLRLQLLAKEEHKLSLLMAESLQHDKVAPVLYQLHLEALDRRLRIVLQAVRDCVEKDGLSSVVEDDLATEHRASTER
Sequence Length
579
Species
Mus musculus (Mouse)
Production Note
Special Offer: The Baculovirus host-expressed protein is manufactured from a stock plasmid containing the protein gene. Baculovirushost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The Baculovirus host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select Baculovirus host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60.4 kDa
NCBI Official Full Name
extracellular serine/threonine protein kinase FAM20C isoform 1
NCBI Official Synonym Full Names
family with sequence similarity 20, member C
NCBI Official Symbol
Fam20c
NCBI Official Synonym Symbols
DMP4; DMP-4; C76981; GEF-CK; mKIAA4081
NCBI Protein Information
extracellular serine/threonine protein kinase FAM20C
UniProt Protein Name
Extracellular serine/threonine protein kinase FAM20C
Protein Family
UniProt Gene Name
Fam20c
UniProt Synonym Gene Names
GEF-CK
Uniprot Description
Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22900076, PubMed:22732358, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion ().
Research Articles on Fam20c
1. family with sequence similarity member 20C is the primary, but not the only, kinase for the SIBLINGs
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Product Notes
The Fam20c fam20c (Catalog #AAA1468100) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 88-579aa; Full Length of Mature Protein. The amino acid sequence is listed below: DFSSDPASNL TSHSLEKLPS AAEPVDHAPR GQEPRSPPPR DPAHRPLLRD PGPRPRVPPP GPSGDGSLLA KLFEHPLYQG AVPPLTEDDV LFNVNSDIRF NPKAAENPDW PHEGAEGAEF LPTGEAAVNL YPNWLKFHIG INRYELYSRH NPAIDALLRD LGSQKITSVA MKSGGTQLKL IMTFQNYGQA LFKPMKQTRE QETPPDFFYF SDYERHNAEI AAFHLDRILD FRRVPPVAGR MINMTKEIRD VTRDKKLWRT FFVSPANNIC FYGECSYYCS TEHALCGRPD QIEGSLAAFL PDLSLAKRKT WRNPWRRSYH KRKKAEWEVD PDYCEEVKQT PPYDSGHRIL DIMDMTVFDF LMGNMDRHHY ETFEKFGNET FIIHLDNGRG FGKYSHDELS ILAPLHQCCR IRRSTYLRLQ LLAKEEHKLS LLMAESLQHD KVAPVLYQLH LEALDRRLRI VLQAVRDCVE KDGLSSVVED DLATEHRAST ER. It is sometimes possible for the material contained within the vial of "Extracellular serine/threonine protein kinase FAM20C (Fam20c), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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