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Western Blot (WB) (Western blot analysis of CCDC98 in human breast tissue lysate in (A) the absence and (B) presence of blocking peptide with CCDC98 antibody at 1 μg/mL.)

CCDC98 Blocking Peptide | FAM175A blocking peptide

CCDC98 Peptide

Gene Names
FAM175A; ABRA1; CCDC98
Applications
Blocking (BL)
Synonyms
CCDC98; CCDC98 Peptide; ABRA1; UNQ496/PRO1013; BRCA1-A complex subunit Abraxas; Coiled-coil domain-containing protein 98; family with sequence similarity 175; member A; FAM175A blocking peptide
Ordering
For Research Use Only!
Form/Format
Liquid
Concentration
200 ug/mL (varies by lot)
Sequence Length
409
Applicable Applications for FAM175A blocking peptide
Blocking (BL)
Application Notes
CCDC98 peptide is used for blocking the activity of CCDC98 antibody.
Species
Human
Buffer
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Location
15 amino acids near the amino terminus of human CCDC98.
Preparation and Storage
Store CCDC98 peptide at -20 degree C, stable for one year.

Western Blot (WB)

(Western blot analysis of CCDC98 in human breast tissue lysate in (A) the absence and (B) presence of blocking peptide with CCDC98 antibody at 1 μg/mL.)

Western Blot (WB) (Western blot analysis of CCDC98 in human breast tissue lysate in (A) the absence and (B) presence of blocking peptide with CCDC98 antibody at 1 μg/mL.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,663 Da
NCBI Official Full Name
BRCA1-A complex subunit Abraxas
NCBI Official Synonym Full Names
family with sequence similarity 175, member A
NCBI Official Symbol
FAM175A
NCBI Official Synonym Symbols
ABRA1; CCDC98
NCBI Protein Information
BRCA1-A complex subunit Abraxas; abraxas protein; coiled-coil domain containing 98; coiled-coil domain-containing protein 98
UniProt Protein Name
BRCA1-A complex subunit Abraxas
Protein Family
UniProt Gene Name
FAM175A
UniProt Synonym Gene Names
ABRA1; CCDC98
UniProt Entry Name
F175A_HUMAN

Uniprot Description

Abraxas: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1. Belongs to the FAM175 family. Abraxas subfamily.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 4q21.23

Cellular Component: nucleus

Molecular Function: protein binding; polyubiquitin binding

Biological Process: positive regulation of DNA repair; double-strand break repair; response to ionizing radiation; chromatin modification; G2/M transition DNA damage checkpoint

Research Articles on FAM175A

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Product Notes

The FAM175A fam175a (Catalog #AAA152761) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CCDC98 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). CCDC98 peptide is used for blocking the activity of CCDC98 antibody. Researchers should empirically determine the suitability of the FAM175A fam175a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC98, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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