Fatty Acid Binding Protein, Epidermal Recombinant Protein | FABP5 recombinant protein

Fatty Acid Binding Protein, Epidermal (E-FABP), Recombinant, Human

Cat. Num. AAA636746

• Gene Names: FABP5; EFABP; KFABP; E-FABP; PAFABP; PA-FABP
• Applications: ELISA
• Purity: Highly Purified; Purified. 95% by SDS-PAGE.
• Synonyms: Fatty Acid Binding Protein; Epidermal; Epidermal (E-FABP); Recombinant; Human; FABP5 recombinant protein

• Host: Human, Recombinant, E Coli
• Purity/Purification: Highly Purified; Purified. 95% by SDS-PAGE.
• Form/Format: Supplied as a liquid.

• Applicable Applications for FABP5 recombinant protein: ELISA (EL/EIA)
• Application Notes: Suitable for use in ELISA., , Recommended Dilution:, Optimal dilutions to be determined by the researcher.
• Preparation and Storage: May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Related Product Information for FABP5 recombinant protein

Recombinant E-FABP comprises a 135 amino acid fragment (1-135) corresponding to the human epidermal FABP protein and is expressed in E. coli with an amino- terminal hexahistidine tag.

Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins (14-15kDa) that bind long chain fatty acids, their CoA derivatives, billiruben, organic anions and other small hydrophobic molecules. E-FABP (or FABP-5) is thought work in conjunction with A-FABP to facilitate fatty acid efflux from adipocytes. E-FABP may also be involved in keratinocyte differentiation.

Product Categories/Family for FABP5 recombinant protein

Molecular Biology; MB-Fatty Acid Binding Protein

NCBI and Uniprot Product Information

• NCBI GI #: 4557581
• NCBI GeneID: 2171
• NCBI Accession #: NP_001435.1
• NCBI GenBank Nucleotide #: NM_001444.2
• UniProt Accession #: Q01469; B2R4K0
• Molecular Weight: 15,164 Da
• NCBI Official Full Name: fatty acid-binding protein, epidermal
• NCBI Official Synonym Full Names: fatty acid binding protein 5 (psoriasis-associated)
• NCBI Official Symbol: FABP5
• NCBI Official Synonym Symbols: EFABP; KFABP; E-FABP; PAFABP; PA-FABP
• NCBI Protein Information: fatty acid-binding protein, epidermal; epidermal-type fatty acid-binding protein; psoriasis-associated fatty acid-binding protein homolog
• UniProt Protein Name: Fatty acid-binding protein, epidermal
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP5
• UniProt Synonym Gene Names: E-FABP; PA-FABP
• UniProt Entry Name: FABP5_HUMAN

NCBI Description

This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]

Uniprot Description

FABP5: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: nucleoplasm; cytoplasm; cytosol

Molecular Function: protein binding; transporter activity; lipid binding; fatty acid binding

Biological Process: epidermis development; phosphatidylcholine biosynthetic process; glucose metabolic process; glucose transport; lipid metabolic process