Fatty Acid Binding Protein 1, Liver (FABP1) Recombinant Protein | FABP1 recombinant protein

Recombinant Fatty Acid Binding Protein 1, Liver (FABP1)

Cat. Num. AAA2009779

• Gene Names: FABP1; FABPL; L-FABP
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 95%
• Synonyms: Fatty Acid Binding Protein 1; Liver (FABP1); Recombinant Fatty Acid Binding Protein 1; FABP1 recombinant protein

• Host: E Coli
• Purity/Purification: > 95%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with N-terminal His-Tag, its sequence is listed below.; MGHHHHHHSGS-SFSGKYQLQ SQENFEAFMK AIGLPEELIQ KGKDIKGVSE IVQNGKHFKF TITAGSKVIQ NEFTVGEECE LETMTGEKVK TVVQLEGDNK LVTTFKNIKS VTELNGDIIT NTMTLGDIVF KRISKRI
• Sequence Length: 127

• Applicable Applications for FABP1 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Homo sapiens (Human)
• Expression System: Prokaryotic expression
• Residues: Ser2~Ile127 (Accession # P07148) with N-terminal His-Tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 4557577
• NCBI GeneID: 2168
• NCBI Accession #: NP_001434.1
• NCBI GenBank Nucleotide #: NM_001443.2
• UniProt Accession #: P07148
• Molecular Weight: 15.3kDa
• NCBI Official Full Name: fatty acid-binding protein, liver
• NCBI Official Synonym Full Names: fatty acid binding protein 1, liver
• NCBI Official Symbol: FABP1
• NCBI Official Synonym Symbols: FABPL; L-FABP
• NCBI Protein Information: fatty acid-binding protein, liver; fatty acid-binding protein 1; liver-type fatty acid-binding protein
• UniProt Protein Name: Fatty acid-binding protein, liver
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP1
• UniProt Synonym Gene Names: FABPL; L-FABP
• UniProt Entry Name: FABPL_HUMAN

NCBI Description

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

Uniprot Description

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p11

Cellular Component: nucleoplasm; peroxisomal matrix; apical cortex; cytosol

Molecular Function: antioxidant activity; bile acid binding; phospholipid binding; chromatin binding; drug binding; long-chain fatty acid transporter activity; fatty acid binding

Biological Process: long-chain fatty acid transport; positive regulation of cell proliferation; positive regulation of hydrolase activity; cellular lipid metabolic process; negative regulation of caspase activity; positive regulation of fatty acid beta-oxidation; intestinal absorption; negative regulation of apoptosis