Chicken eyes absent homolog 1 (Drosophila) ELISA Kit | EYA1 elisa kit
Chicken Eyes absent homolog 1, EYA1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Function: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for other transcription factors of this family. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Has also phosphatase activity with proteins phosphorylated on Ser and Thr residues (in vitro). Required for normal embryonic development of the skeleton, kidneys and ears
Catalytic activity: Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
Cofactor: Binds 1 Mg2+ ion per subunit
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Product Notes
The Chicken EYA1 eya1 (Catalog #AAA9327160) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9327160 ELISA Kit recognizes Chicken EYA1. It is sometimes possible for the material contained within the vial of "eyes absent homolog 1 (Drosophila), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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