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Electron Transfer Flavoprotein Alpha Polypeptide (ETFa) Recombinant Protein | ETFa recombinant protein
Recombinant Electron Transfer Flavoprotein Alpha Polypeptide (ETFa)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-APITLNT ITAAGRLGGE VSCLVAGTKC DKVVQDLCKV AGVAKVLVAQ HDAYKGLLPE ELTPLILETQ KQFSYTHICA GASAFGKNLL PRVAAKLNVA PVSDIIEIKS PDTFVRTIYA GNALCTVKCD EKVKVFSVRG TSFEAAAASG GSASSEKAPS SSSAGISEWL DQKLTKSDRP ELTGAKVVVS GGRGLKSGEN FKLLYDLADQ LHAAVGASRA AVDAGFVPND MQVGQTGKIV APELYIAVGI SGAIQHLAGM KDSKT
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
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SDS-Page
NCBI and Uniprot Product Information
NCBI Description
specific electron acceptor for several dehydrogenases, including acyl-coA dehyrogenases, glutaryl-coA and sarcosine dehydrogenase; transfers electrons to the main mitochondrial respiratory chain [RGD, Feb 2006]
Uniprot Description
ETFA: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl- CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). Defects in ETFA are the cause of glutaric aciduria type 2A (GA2A); also known as glutaricaciduria IIA. GA2A is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Belongs to the ETF alpha-subunit/FixB family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; Mitochondrial
Cellular Component: mitochondrion; mitochondrial matrix
Molecular Function: FAD binding; electron carrier activity; oxidoreductase activity
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Product Notes
The ETFa etfa (Catalog #AAA2009847) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Electron Transfer Flavoprotein Alpha Polypeptide (ETFa) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the ETFa etfa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-API TLNT ITAAGRLGGE VSCLVAGTKC DKVVQDLCKV AGVAKVLVAQ HDAYKGLLPE ELTPLILETQ KQFSYTHICA GASAFGKNLL PRVAAKLNVA PVSDIIEIKS PDTFVRTIYA GNALCTVKCD EKVKVFSVRG TSFEAAAASG GSASSEKAPS SSSAGISEWL DQKLTKSDRP ELTGAKVVVS GGRGLKSGEN FKLLYDLADQ LHAAVGASRA AVDAGFVPND MQVGQTGKIV APELYIAVGI SGAIQHLAGM KDSKT. It is sometimes possible for the material contained within the vial of "Electron Transfer Flavoprotein Alpha Polypeptide (ETFa), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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