Exfoliative toxin A Recombinant Protein | eta recombinant protein

Recombinant Staphylococcus aureus Exfoliative toxin A (eta)

Cat. Num. AAA1223672

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Exfoliative toxin A; Recombinant Staphylococcus aureus Exfoliative toxin A (eta); Epidermolytic toxin A; eta recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 39-280aa; Full Length of Mature Protein
• Sequence: EVSAEEIKKHEEKWNKYYGVNAFNLPKELFSKVDEKDRQKYPYNTIGNVFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEILQEPFGAGVDLALIRLKPDQNGVSLGDKISPAKIGTSNDLKDGDKLELIGYPFDHKVNQMHRSEIELTTLSRGLRYYGFTVPGNSGSGIFNSNGELVGIHSSKVSHLDREHQINYGVGIGNYVKRIINEKNE

• Production Note: Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
• Preparation and Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-Page

Related Product Information for eta recombinant protein

Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS).

References

Sequence determination and comparison of the exfoliative toxin A and toxin B genes from Staphylococcus aureus.Lee C.Y., Schmidt J.J., Johnson-Winegar A.D., Spero L., Iandolo J.J.J. Bacteriol. 169:3904-3909(1987) Nucleotide sequence of the epidermolytic toxin A gene of Staphylococcus aureus.O'Toole P.W., Foster T.J.J. Bacteriol. 169:3910-3915(1987) DNA sequencing of the eta gene coding for staphylococcal exfoliative toxin serotype A.Sakurai S., Suzuki H., Kondo I.J. Gen. Microbiol. 134:711-717(1988) The reactive serine residue of epidermolytic toxin A.Bailey C.J., Smith T.P.Biochem. J. 269:535-537(1990) The epidermolytic toxins are serine proteases.Dancer S.J., Garrat R., Saldanha J., Jhoti H., Evans R.FEBS Lett. 268:129-132(1990) The role of the serine protease active site in the mode of action of epidermolytic toxin of Staphylococcus aureus.Redpath M.B., Foster T.J., Bailey C.J.FEMS Microbiol. Lett. 65:151-155(1991) The structure of the superantigen exfoliative toxin A suggests a novel regulation as a serine protease.Vath G.M., Earhart C.A., Rago J.V., Kim M.H., Bohach G.A., Schlievert P.M., Ohlendorf D.H.Biochemistry 36:1559-1566(1997) The structure of Staphylococcus aureus epidermolytic toxin A, an atypic serine protease, at 1.7-A resolution.Cavarelli J., Prevost G., Bourguet W., Moulinier L., Chevrier B., Delagoutte B., Bilwes A., Mourey L., Rifai S., Piemont Y., Moras D.Structure 5:813-824(1997)

NCBI and Uniprot Product Information

• NCBI GI #: 446988525
• NCBI Accession #: WP_001065781.1
• NCBI GenBank Nucleotide #: WP_001065781.1
• UniProt Accession #: P09331
• Molecular Weight: 30.9 kDa
• NCBI Official Full Name: exfoliative toxin A
• UniProt Protein Name: Exfoliative toxin A
• Protein Family: Exotoxin
• UniProt Gene Name: eta
• UniProt Entry Name: ETA_STAAU

Uniprot Description

Has serine protease-like properties and binds to the skin protein profilaggrin. Cleaves substrates after acidic residues. Exfoliative toxins cause impetigous diseases commonly referred as staphylococcal scalded skin syndrome (SSSS).