Mouse extra spindle pole bodies homolog 1 (S. cerevisiae) ELISA Kit | ESPL1 elisa kit
Mouse Separin, ESPL1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
separase: a caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms. Regulated by at least two independent mechanisms. First, it is inactivated via its interaction with securin/PTTG1, which probably covers its active site. Second, phosphorylation inactivates it. It is completely phosphorylated during mitosis and dephosphorylated during anaphase. Two alternatively spliced isoforms have been described.
Protein type: EC 3.4.22.49; Protease
Cellular Component: centrosome; cytoplasm; nucleus
Molecular Function: peptidase activity; hydrolase activity; cysteine-type peptidase activity
Biological Process: mitosis; homologous chromosome segregation; mitotic sister chromatid segregation; proteolysis; meiotic spindle organization and biogenesis; meiosis I; chromosome segregation
Research Articles on ESPL1
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Product Notes
The Mouse ESPL1 espl1 (Catalog #AAA9318599) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9318599 ELISA Kit recognizes Mouse ESPL1. It is sometimes possible for the material contained within the vial of "extra spindle pole bodies homolog 1 (S. cerevisiae), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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