SDS-Page
Endogenous retrovirus group K member 6 Env polyprotein (ERVK-6) Recombinant Protein | ERVK-6 recombinant protein
Recombinant Human Endogenous retrovirus group K member 6 Env polyprotein (ERVK-6), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Endogenous retrovirus group K member 6 Env polyprotein (ERVK-6); Recombinant Human Endogenous retrovirus group K member 6 Env polyprotein (ERVK-6); partial; EnvK2 protein; Envelope polyprotein; HERV-K(C7) envelope protein; HERV-K(HML-2.HOM) envelope protein; HERV-K108 envelope protein;HERV-K_7p22.1 provirus ancestral Env polyprotein; Cleaved into the following 2 chains: Surface proten; SU; Transmembrane protein; TM; ERVK-6 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
90-632aa; Extracellular Domain
Sequence
LPMPAGAAAANYTYWAYVPFPPLIRAVTWMDNPTEVYVNDSVWVPGPIDDRCPAKPEEEGMMINISIGYHYPPICLGRAPGCLMPAVQNWLVEVPTVSPICRFTYHMVSGMSLRPRVNYLQDFSYQRSLKFRPKGKPCPKEIPKESKNTEVLVWEECVANSAVILQNNEFGTIIDWAPRGQFYHNCSGQTQSCPSAQVSPAVDSDLTESLDKHKHKKLQSFYPWEWGEKGISTPRPKIVSPVSGPEHPELWRLTVASHHIRIWSGNQTLETRDRKPFYTIDLNSSLTVPLQSCVKPPYMLVVGNIVIKPDSQTITCENCRLLTCIDSTFNWQHRILLVRAREGVWIPVSMDRPWEASPSVHILTEVLKGVLNRSKRFIFTLIAVIMGLIAVTATAAVAGVALHSSVQSVNFVNDWQKNSTRLWNSQSSIDQKLANQINDLRQTVIWMGDRLMSLEHRFQLQCDWNTSDFCITPQIYNESEHHWDMVRRHLQGREDNLTLDISKLKEQIFEASKAHLNLVPGTEAIAGVADGLANLNPVTWVKT
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
SDS-Page
SDS-Page
Related Product Information for ERVK-6 recombinant protein
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties.
SU mediates receptor recognition.
TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane
References
"Identification of a Rev-related protein by analysis of spliced transcripts of the human endogenous retroviruses HTDV/HERV-K."
Loewer R., Toenjes R.R., Korbmacher C., Kurth R., Loewer J.
J. Virol. 69:141-149(1995)
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
63.5 kDa
NCBI Official Full Name
Endogenous retrovirus group K member 6 Env polyprotein
UniProt Protein Name
Endogenous retrovirus group K member 6 Env polyprotein
Protein Family
UniProt Gene Name
ERVK-6
UniProt Synonym Gene Names
ERVK6; SU; TM
UniProt Entry Name
ENK6_HUMAN
Uniprot Description
ERVK6: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties. Belongs to the beta type-B retroviral envelope protein family. HERV class-II K(HML-2) env subfamily.
Protein type: Protease; EC 3.1.26.4; Ribonuclease; Membrane protein, integral; EC 2.7.7.7; EC 3.4.23.16; EC 2.7.7.49; EC 3.4.23.-; Transferase
Chromosomal Location of Human Ortholog: 7p22.1
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Product Notes
The ERVK-6 ervk-6 (Catalog #AAA1391552) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 90-632aa; Extracellular Domain. The amino acid sequence is listed below: LPMPAGAAAA NYTYWAYVPF PPLIRAVTWM DNPTEVYVND SVWVPGPIDD RCPAKPEEEG MMINISIGYH YPPICLGRAP GCLMPAVQNW LVEVPTVSPI CRFTYHMVSG MSLRPRVNYL QDFSYQRSLK FRPKGKPCPK EIPKESKNTE VLVWEECVAN SAVILQNNEF GTIIDWAPRG QFYHNCSGQT QSCPSAQVSP AVDSDLTESL DKHKHKKLQS FYPWEWGEKG ISTPRPKIVS PVSGPEHPEL WRLTVASHHI RIWSGNQTLE TRDRKPFYTI DLNSSLTVPL QSCVKPPYML VVGNIVIKPD SQTITCENCR LLTCIDSTFN WQHRILLVRA REGVWIPVSM DRPWEASPSV HILTEVLKGV LNRSKRFIFT LIAVIMGLIA VTATAAVAGV ALHSSVQSVN FVNDWQKNST RLWNSQSSID QKLANQINDL RQTVIWMGDR LMSLEHRFQL QCDWNTSDFC ITPQIYNESE HHWDMVRRHL QGREDNLTLD ISKLKEQIFE ASKAHLNLVP GTEAIAGVAD GLANLNPVTW VKT . It is sometimes possible for the material contained within the vial of "Endogenous retrovirus group K member 6 Env polyprotein (ERVK-6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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