Human EPH receptor A7 ELISA Kit | EPHA7 elisa kit
Human Ephrin type-A receptor 7, EPHA7 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
EphA7: a widely-expressed receptor tyrosine kinase of the Eph family. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5. Contains 1 sterile alpha motif (SAM) and two fibronectin type III domains.
Protein type: EC 2.7.10.1; Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (receptor); Membrane protein, integral; TK group; Eph family
Chromosomal Location of Human Ortholog: 6q16.1
Cellular Component: postsynaptic membrane; cell soma; integral to plasma membrane; dendrite; plasma membrane; neuromuscular junction
Molecular Function: protein binding; ephrin receptor binding; GPI-linked ephrin receptor activity; chemorepellent activity; protein-tyrosine kinase activity; axon guidance receptor activity; ATP binding
Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; regulation of cell-cell adhesion; branching morphogenesis of a nerve; positive regulation of neuron apoptosis; regulation of protein amino acid autophosphorylation; ephrin receptor signaling pathway; negative chemotaxis; brain development; regulation of caspase activity; phosphorylation; regulation of peptidyl-tyrosine phosphorylation; retinal ganglion cell axon guidance
Research Articles on EPHA7
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Product Notes
The Human EPHA7 epha7 (Catalog #AAA9321322) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9321322 ELISA Kit recognizes Human EPHA7. It is sometimes possible for the material contained within the vial of "EPH receptor A7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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