SDS-Page
EPGN recombinant protein
EPGN, 23-110aa, Human, His-tag, Baculovirus
Gene Names
EPGN; EPG; PRO9904; ALGV3072
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
EPGN; 23-110aa; Human; His-tag; Baculovirus; Epigen isoform 1; ALGV3072; EPG; PRO9904; EPGN recombinant protein
Host
Baculovirus
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
Concentration
0.5 mg/ml (determined by Absorbance at 280nm) (varies by lot)
Sequence
ADPAAVTVTP PITAQQGNWT VNKTEADNIE GPIALKFSHL CLEDHNSYCI NGACAFHHEL EKAICRCFTG YTGERCEHLT LTSYAVDSYE KHHHHHH
Sequence Length
154
Applicable Applications for EPGN recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Endotoxin Level
< 1.0 EU per 1ug of protein (determined by LAL method)
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for EPGN recombinant protein
EPGN, also known as epigen isoform 1, is a novel member of the epidermal growth factor superfamily. It is the last ligand of ErbB receptors and reveals intricate relationships between affinity and mitogenicity. It stimulated the proliferation of HaCaT cells, and this proliferation was blocked by an antibody to the extracellular domain of the receptor tyrosine kinase c-erbB-1. It also may constitute a novel molecular target for wound-healing therapy with its ability to promote the growth of epithelial cells. It has been reported to have high mitogenic activity but low affinity for its receptor. It has been reported in cancer specimens of the breast, bladder, and prostate. Recombinant human EPGN, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Product Categories/Family for EPGN recombinant protein
References
Kochupurakkal BS., et al. (2005) J Biol Chem. 280:8503-8512.; Strachan L., et al. (2001) J Biol Chem. 276:18265-18271.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10.8kDa (97aa) 13.5-18kDa (SDS-PAGE under reducing conditions)
NCBI Official Full Name
epigen isoform 1
NCBI Official Synonym Full Names
epithelial mitogen
NCBI Official Symbol
EPGN
NCBI Official Synonym Symbols
EPG; PRO9904; ALGV3072
NCBI Protein Information
epigen
UniProt Protein Name
Epigen
Protein Family
UniProt Gene Name
EPGN
UniProt Synonym Gene Names
EPG
NCBI Description
The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Uniprot Description
Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Research Articles on EPGN
Similar Products
Product Notes
The EPGN epgn (Catalog #AAA206732) is a Recombinant Protein produced from Baculovirus and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's EPGN can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the EPGN epgn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ADPAAVTVTP PITAQQGNWT VNKTEADNIE GPIALKFSHL CLEDHNSYCI NGACAFHHEL EKAICRCFTG YTGERCEHLT LTSYAVDSYE KHHHHHH. It is sometimes possible for the material contained within the vial of "EPGN, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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