Mouse erythrocyte membrane protein band 4.2 ELISA Kit | EPB42 elisa kit
Mouse Erythrocyte membrane protein band 4.2, EPB42 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is the key component of a macromolecular complex involved in the structure of erythrocytes. [provided by RefSeq, Aug 2015]
Uniprot Description
Epb4.2: Probably plays an important role in the regulation of erythrocyte shape and mechanical properties. Defects in EPB42 are the cause of spherocytosis type 5 (SPH5); also known as hereditary spherocytosis type 5 (HS5). Spherocytosis is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. Absence of band 4.2 associated with spur or target erythrocytes has also been reported. Belongs to the transglutaminase superfamily. Transglutaminase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Cellular Component: cortical cytoskeleton; cytoskeleton; membrane; cytoplasm; plasma membrane
Molecular Function: protein-glutamine gamma-glutamyltransferase activity
Biological Process: spleen development; regulation of cell shape; iron ion homeostasis; erythrocyte maturation; ion homeostasis; hemoglobin metabolic process; cell morphogenesis; peptide cross-linking
Research Articles on EPB42
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Product Notes
The Mouse EPB42 epb42 (Catalog #AAA9316429) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9316429 ELISA Kit recognizes Mouse EPB42. It is sometimes possible for the material contained within the vial of "erythrocyte membrane protein band 4.2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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