Mouse Ectonucleoside triphosphate diphosphohydrolase 5 ELISA Kit | Entpd5 elisa kit
Mouse Ectonucleoside triphosphate diphosphohydrolase 5 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ENTPD5: Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling. Belongs to the GDA1/CD39 NTPase family.
Protein type: Nucleotide Metabolism - purine; EC 3.6.1.42; Nucleotide Metabolism - pyrimidine; EC 3.6.1.6; Oncoprotein; Hydrolase
Cellular Component: endoplasmic reticulum; extracellular region
Molecular Function: guanosine-diphosphatase activity; hydrolase activity; nucleoside-diphosphatase activity; uridine-diphosphatase activity
Biological Process: 'de novo' posttranslational protein folding; ATP metabolic process; cell growth; cell proliferation; positive regulation of glycolysis; protein amino acid N-linked glycosylation; regulation of phosphoinositide 3-kinase cascade
Research Articles on Entpd5
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Product Notes
The Mouse Entpd5 entpd5 (Catalog #AAA2883224) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883224 ELISA Kit recognizes Mouse Entpd5. It is sometimes possible for the material contained within the vial of "Ectonucleoside triphosphate diphosphohydrolase 5, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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