Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (Enpp6) Recombinant Protein | Enpp6 recombinant protein
Recombinant Mouse Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (Enpp6)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the nucleotide pyrophosphatase/phosphodiesterase family of enzymes that play an important role in regulating extracellular nucleotide metabolism. The encoded preproprotein undergoes proteolytic processing to generate a glycosylphosphatidylinositol (GPI)-anchored membrane protein that hydrolyzes choline-containing lysophospholipids such as glycerophosphocholine. Mice lacking the encoded protein develop fatty liver and myelin sheath abnormalities. [provided by RefSeq, Jul 2016]
Uniprot Description
Choline-specific glycerophosphodiester phosphodiesterase. The preferred substrate may be lysosphingomyelin (). Hydrolyzes lysophosphatidylcholine (LPC) to form monoacylglycerol and phosphorylcholine but not lysophosphatidic acid, showing it has a lysophospholipase C activity. Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids. Also hydrolyzes glycerophosphorylcholine and sphingosylphosphorylcholine efficiently. Hydrolyzes the classical substrate for phospholipase C, p-nitrophenyl phosphorylcholine in vitro, while it does not hydrolyze the classical nucleotide phosphodiesterase substrate, p-nitrophenyl thymidine 5'-monophosphate. Does not hydrolyze diacyl phospholipids such as phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine, phosphatidylglycerol and phosphatidic acid ().
Research Articles on Enpp6
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Product Notes
The Enpp6 enpp6 (Catalog #AAA1369320) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 23-419, Full length protein. The amino acid sequence is listed below: HRKLLVLLLD GFRSDYISED ALASLPGFRE IVNRGVKVDY LTPDFPSLSY PNYYTLMTGR HCEVHQMIGN YMWDPRTNKS FDIGVNRDSL MPLWWNGSEP LWITLMKARR KVYMYYWPGC EVEILGVRPT YCLEYKTVPT DINFANAVSD ALDSLKSGRA DLAAIYHERI DVEGHHYGPS SPQRKDALRA VDTVLKYMIQ WIQDRGLQQD LNVILFSDHG MTDIFWMDKV IELSNYISLD DLQQVKDRGP VVSLWPVPGK HSEIYHKLRT VEHMTVYEKE SIPNRFYYKK GKFVSPLTLV ADEGWFIAES REMLPFWMNS TGKREGWQRG WHGYDNELMD MRGIFLAIGP DFKSNFRAAP IRSVDVYNIM CHVAGITPLP NNGSWSRVVC MLKGQTS. It is sometimes possible for the material contained within the vial of "Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 (Enpp6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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