Typical Testing Data/Standard Curve (for reference only)
Mouse ectonucleotide pyrophosphatase/phosphodiesterase 2 ELISA Kit | ENPP2 elisa kit
Mouse Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, ENPP2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
ENPP2: Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility- related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Lipid Metabolism - ether lipid; EC 3.1.4.39; Phosphodiesterase
Cellular Component: Golgi apparatus; extracellular space; integral to plasma membrane; cytoplasm; extracellular region
Molecular Function: phosphodiesterase I activity; nucleotide diphosphatase activity; nucleic acid binding; hydrolase activity; zinc ion binding; metal ion binding; calcium ion binding; catalytic activity; scavenger receptor activity; alkylglycerophosphoethanolamine phosphodiesterase activity; lysophospholipase activity; polysaccharide binding
Biological Process: positive regulation of focal adhesion formation; phospholipid catabolic process; metabolic process; positive regulation of cell proliferation; immune response; positive regulation of oligodendrocyte differentiation; lipid metabolic process; negative regulation of cell-matrix adhesion; chemotaxis; regulation of angiogenesis; regulation of cell migration; lipid catabolic process
Research Articles on ENPP2
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Product Notes
The Mouse ENPP2 enpp2 (Catalog #AAA907475) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA907475 ELISA Kit recognizes Mouse ENPP2. It is sometimes possible for the material contained within the vial of "ectonucleotide pyrophosphatase/phosphodiesterase 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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