Typical Testing Data/Standard Curve (for reference only)
Mouse Endoglin ELISA Kit | Eng elisa kit
Mouse Endoglin ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
ENG: Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Homodimer that forms an heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It is able to bind TGF-beta 1, and 3 efficiently and TGF-beta 2 less efficiently. Interacts with TCTEX1D4. Interacts with ARRB2. Endoglin is restricted to endothelial cells in all tissues except bone marrow. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Receptor, misc.; Membrane protein, integral
Cellular Component: cell surface; cytoplasm; external side of plasma membrane; extracellular space; focal adhesion; integral to membrane; membrane; nucleoplasm; receptor complex
Molecular Function: galactose binding; glycosaminoglycan binding; protein binding; protein homodimerization activity; punt binding; transforming growth factor beta binding; transforming growth factor beta receptor activity; transforming growth factor beta receptor, cytoplasmic mediator activity
Biological Process: angiogenesis; artery morphogenesis; cell adhesion; cell migration; cell motility involved in cell locomotion; central nervous system vasculogenesis; extracellular matrix disassembly; heart development; heart looping; negative regulation of cell migration; negative regulation of endothelial cell proliferation; negative regulation of nitric-oxide synthase activity; negative regulation of protein amino acid autophosphorylation; negative regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; positive regulation of angiogenesis; positive regulation of BMP signaling pathway; positive regulation of collagen biosynthetic process; positive regulation of protein amino acid phosphorylation; positive regulation of systemic arterial blood pressure; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; regulation of transforming growth factor beta receptor signaling pathway; response to hypoxia; smooth muscle development; transforming growth factor beta receptor signaling pathway; vasculogenesis; venous blood vessel morphogenesis; wound healing
Research Articles on Eng
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Product Notes
The Mouse Eng eng (Catalog #AAA2885491) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2885491 ELISA Kit recognizes Mouse Eng. It is sometimes possible for the material contained within the vial of "Endoglin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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