ADGRE1 recombinant protein

Recombinant Human ADGRE1

Gene Names

EMR1; TM7LN3

Applications

Western Blot, ELISA

Purity

Greater than 95% by SDS-PAGE gel analyses

Synonyms

ADGRE1; Recombinant Human ADGRE1; Adhesion G protein-coupled receptor E1; EGF like module receptor 1; EMR1; EMR1 hormone receptor; F4/80; TM7LN3; ADGRE1 recombinant protein

Ordering
Cat. Num. AAA7613632 For Research Use Only!

Host

E Coli

Purity/Purification

Greater than 95% by SDS-PAGE gel analyses

Form/Format

Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4

Sequence Positions

376-506

Applicable Applications for ADGRE1 recombinant protein

Western Blot (WB), ELISA (EIA)

Species

Human

Tag

N-terminal His-IF2DI Tag

Reconstitution

Centrifuge the vial at 10,000rpm for 1 minute, reconstitute at 200ug/ml in sterile distilled water

Preparation and Storage

Store at -20 degree C for 12 months as lyophilized; 2-8 degree C for 1 month under sterile conditions after reconstitution

NCBI and Uniprot Product Information

NCBI GI #

372266078

NCBI GeneID

2015

NCBI Accession #

NP_001243181.1

NCBI GenBank Nucleotide #

NM_001256252.1

UniProt Accession #

Q14246; Q2I7G5; Q6ZMN0; Q8NGA7; A6NHV2; B7Z486; B7Z489; E7EPX9; E9PD45; H9KV79

Molecular Weight

97,683 Da

NCBI Official Full Name

EGF-like module-containing mucin-like hormone receptor-like 1 isoform 2

NCBI Official Synonym Full Names

egf-like module containing, mucin-like, hormone receptor-like 1

NCBI Official Symbol

EMR1

NCBI Official Synonym Symbols

TM7LN3

NCBI Protein Information

EGF-like module-containing mucin-like hormone receptor-like 1; EMR1 hormone receptor; EGF-like module receptor 1; egf-like module containing, mucin-like, hormone receptor-like sequence 1

UniProt Protein Name

EGF-like module-containing mucin-like hormone receptor-like 1

Protein Family

Adhesion G protein-coupled receptor

UniProt Gene Name

EMR1

UniProt Synonym Gene Names

TM7LN3

UniProt Entry Name

EMR1_HUMAN

NCBI Description

This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Uniprot Description

EMR1: Could be involved in cell-cell interactions. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: integral to plasma membrane; external side of plasma membrane

Molecular Function: G-protein coupled receptor activity; calcium ion binding

Biological Process: G-protein coupled receptor protein signaling pathway; cell adhesion

Research Articles on ADGRE1

1. Additional transcription changes likely associated with Th2-like eosinophilic inflammation were prominent and included increased EMR1&3.

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Product Notes

The ADGRE1 emr1 (Catalog #AAA7613632) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 376-506. AAA Biotech's ADGRE1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Researchers should empirically determine the suitability of the ADGRE1 emr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADGRE1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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