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Probable crossover junction endonuclease EME2 (EME2) Recombinant Protein | EME2 recombinant protein

Recombinant Human Probable crossover junction endonuclease EME2 (EME2)

Gene Names
EME2; SLX2B; gs125
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Probable crossover junction endonuclease EME2 (EME2); Recombinant Human Probable crossover junction endonuclease EME2 (EME2); EME2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-379, Full length protein
Sequence
MARVGPGRAGVSCQGRGRGRGGSGQRRPPTWEISDSDAEDSAGSEAAARARDPAGERRAAAEALRLLRPEQVLKRLAVCVDTAILEDAGADVLMEALEALGCECRIEPQRPARSLRWTRASPDPCPRSLPPEVWAAGEQELLLLLEPEEFLQGVATLTQISGPTHWVPWISPETTARPHLAVIGLDAYLWSRQHVSRGTQQPESPKVAGAEVAVSWPEVEEVRACLSWALVLLQLWANLDVLLVASWQELSRHVCAVTKALAQYPLKGGRITSRQYRESQAFSFCTAGRWAAGEPVARDGAGLQAAWRRQIRQFSRVSPAVADAVVTAFPSPRLLQQALEACSTERERMGLLAVGPDLSRRICLFLTTANPDLLLDLGS
Sequence Length
379
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,446 Da
NCBI Official Full Name
probable crossover junction endonuclease EME2
NCBI Official Synonym Full Names
essential meiotic structure-specific endonuclease subunit 2
NCBI Official Symbol
EME2
NCBI Official Synonym Symbols
SLX2B; gs125
NCBI Protein Information
probable crossover junction endonuclease EME2
UniProt Protein Name
Probable crossover junction endonuclease EME2
UniProt Gene Name
EME2

NCBI Description

EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]

Uniprot Description

Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures.

Research Articles on EME2

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Product Notes

The EME2 eme2 (Catalog #AAA1038253) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-379, Full length protein. The amino acid sequence is listed below: MARVGPGRAG VSCQGRGRGR GGSGQRRPPT WEISDSDAED SAGSEAAARA RDPAGERRAA AEALRLLRPE QVLKRLAVCV DTAILEDAGA DVLMEALEAL GCECRIEPQR PARSLRWTRA SPDPCPRSLP PEVWAAGEQE LLLLLEPEEF LQGVATLTQI SGPTHWVPWI SPETTARPHL AVIGLDAYLW SRQHVSRGTQ QPESPKVAGA EVAVSWPEVE EVRACLSWAL VLLQLWANLD VLLVASWQEL SRHVCAVTKA LAQYPLKGGR ITSRQYRESQ AFSFCTAGRW AAGEPVARDG AGLQAAWRRQ IRQFSRVSPA VADAVVTAFP SPRLLQQALE ACSTERERMG LLAVGPDLSR RICLFLTTAN PDLLLDLGS. It is sometimes possible for the material contained within the vial of "Probable crossover junction endonuclease EME2 (EME2), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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