Western Blot (WB)
(Western Blot analysis of EME2 in 231 cell lysate using EME2 Rabbit pAb at dilution 1/200)
Rabbit anti-Human EME2 Polyclonal Antibody | anti-EME2 antibody
EME2 Rabbit pAb
IHC-P: 1:30-1:150
Western Blot (WB)
(Western Blot analysis of EME2 in 231 cell lysate using EME2 Rabbit pAb at dilution 1/200)
Western Blot (WB)
(Western Blot analysis of EME2 in 231 cell lysate using EME2 Rabbit pAb at dilution 1/200)
Immunohistochemistry (IHC)
(Immunohistochemistry of EME2 in paraffin-embedded Human thyroid cancer tissue using EME2 Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm or Nucleus)
Immunohistochemistry (IHC)
(Immunohistochemistry of EME2 in paraffin-embedded Human thyroid cancer tissue using EME2 Rabbit pAb at dilution 1/25. Predicted cell location: Cytoplasm or Nucleus)
NCBI and Uniprot Product Information
NCBI Description
EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]
Uniprot Description
EME2: Interacts with MUS81 to form a DNA structure-specific endonuclease which cleaves substrates such as 3'-flap structures. Belongs to the EME1/MMS4 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Deoxyribonuclease; EC 3.1.22.-
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component: nuclear chromatin
Molecular Function: crossover junction endodeoxyribonuclease activity; DNA binding
Biological Process: double-strand break repair; intra-S DNA damage checkpoint; replication fork processing; resolution of meiotic recombination intermediates
Research Articles on EME2
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Product Notes
The EME2 eme2 (Catalog #AAA4760877) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EME2 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EME2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000 IHC-P: 1:30-1:150. Researchers should empirically determine the suitability of the EME2 eme2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EME2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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