ELOVL1 / Elongation Of Very Long Chain Fatty Acids Protein 1 Recombinant Protein | ELOVL1 recombinant protein
Human ELOVL1 / Elongation Of Very Long Chain Fatty Acids Protein 1 Recombinant Protein
Gene Names
ELOVL1; Ssc1; IKSHD; CGI-88
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
ELOVL1 / Elongation Of Very Long Chain Fatty Acids Protein 1; Human ELOVL1 / Elongation Of Very Long Chain Fatty Acids Protein 1 Recombinant Protein; Elongation of very long chain fatty acids protein 1; 3-keto acyl-CoA synthase ELOVL1; ELOVL fatty acid elongase 1; ELOVL FA elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1; SSC1; CGI-88; ELOVL1 recombinant protein
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
279
Applicable Applications for ELOVL1 recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Interacts with LASS2, TECR and HSD17B12.
Entry Function
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
elongation of very long chain fatty acids protein 1 isoform 1
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 1
NCBI Official Symbol
ELOVL1
NCBI Official Synonym Symbols
Ssc1; IKSHD; CGI-88
NCBI Protein Information
elongation of very long chain fatty acids protein 1
UniProt Protein Name
Elongation of very long chain fatty acids protein 1
Protein Family
UniProt Gene Name
ELOVL1
UniProt Synonym Gene Names
SSC1; ELOVL FA elongase 1
UniProt Entry Name
ELOV1_HUMAN
Uniprot Description
ELOVL1: Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Belongs to the ELO family.
Protein type: EC 2.3.1.199; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p34.2
Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to endoplasmic reticulum membrane
Molecular Function: protein binding; fatty acid elongase activity
Biological Process: sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; fatty acid elongation, saturated fatty acid
Research Articles on ELOVL1
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Product Notes
The ELOVL1 elovl1 (Catalog #AAA2902483) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ELOVL1 / Elongation Of Very Long Chain Fatty Acids Protein 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the ELOVL1 elovl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELOVL1 / Elongation Of Very Long Chain Fatty Acids Protein 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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