ELMD2 Blocking Peptide | ELMOD2 blocking peptide

ELMD2 Antibody (C-term) Blocking peptide

• Gene Names: ELMOD2; 9830169G11Rik
• Synonyms: ELMD2; ELMD2 Antibody (C-term) Blocking peptide; ELMO domain-containing protein 2; ELMOD2; ELMOD2 blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 293

• Tissue Location: Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for ELMOD2 blocking peptide

Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.

NCBI and Uniprot Product Information

• NCBI GI #: 74728441
• NCBI GeneID: 255520
• UniProt Accession #: Q8IZ81; B2R712; D3DNZ0
• Molecular Weight: 34,961 Da
• NCBI Official Full Name: ELMO domain-containing protein 2
• NCBI Official Synonym Full Names: ELMO domain containing 2
• NCBI Official Symbol: ELMOD2
• NCBI Official Synonym Symbols: 9830169G11Rik
• NCBI Protein Information: ELMO domain-containing protein 2
• UniProt Protein Name: ELMO domain-containing protein 2
• Protein Family: ELMO domain-containing protein
• UniProt Gene Name: ELMOD2
• UniProt Entry Name: ELMD2_HUMAN

NCBI Description

This gene encodes one of six engulfment and motility (ELMO) domain-containing proteins. This gene is thought to play a role in antiviral responses. Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis. [provided by RefSeq, Sep 2010]

Uniprot Description

ELMOD2: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.

Chromosomal Location of Human Ortholog: 4q31.1

Cellular Component: membrane

Molecular Function: GTPase activator activity

Biological Process: regulation of defense response to virus

Disease: Pulmonary Fibrosis, Idiopathic