Eukaryotic initiation factor 4A-II Recombinant Protein | IF4A2 recombinant protein
Recombinant Human Eukaryotic initiation factor 4A-II protein
NCBI and Uniprot Product Information
Uniprot Description
EIF4A2: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. Belongs to the DEAD box helicase family. eIF4A subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.6.4.13; Helicase; RNA-binding; Translation; Translation initiation
Chromosomal Location of Human Ortholog: 3q27.3
Cellular Component: cytosol; eukaryotic translation initiation factor 4F complex; nucleolus; perinuclear region of cytoplasm
Molecular Function: ATP-dependent RNA helicase activity; ATPase activity; helicase activity; protein binding; RNA binding
Biological Process: poly(A) tail shortening; regulation of translational initiation; RNA secondary structure unwinding; translational initiation
Research Articles on IF4A2
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Product Notes
The IF4A2 eif4a2 (Catalog #AAA9421522) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Full Length, 1-407aa. The Recombinant Human Eukaryotic initiation factor 4A-II protein reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Eukaryotic initiation factor 4A-II, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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