Sterile alpha and TIR motif-containing protein 1 (Ect4) Recombinant Protein | Ect4 recombinant protein
Recombinant Drosophila melanogaster Sterile alpha and TIR motif-containing protein 1 (Ect4), partial
Gene Names
Ect4; anon-WO0118547.272; CG13680; CG13681; CG34373; CG43119; CG7905; CG7915; DmelCG43119; dsarm; dSarm; ect4; Ect4/SARM
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Sterile alpha and TIR motif-containing protein 1 (Ect4); Recombinant Drosophila melanogaster Sterile alpha and TIR motif-containing protein 1 (Ect4); partial; Ect4 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
687-981. Partial
Sequence
VPLWSVEDVQEWVKQIGFNDYIDKFNESQVDGDLLLKLNQDNLRADIGIGNGILLKRFERELQNLKRMADYSSKDTAKMHQFLSEIGTDYCTYTYAMLNAGIDKCALPHVNEDMLMTECGIHNSIHRLRILNAVKNLENSLPSSSEENMAKTLDVFVSYRRSNGSQLASLLKVHLQLRGFSVFIDVERLEAGKFDNGLLNSIRQAKNFVLVLTPDALHRCINDEDCKDWVHREIVAALNSNCNIIPIIDQQFDWPEVERLPEDMRSVAHFNGVNWIHDYQDACIDKLERFLRGEK
Species
Drosophila melanogaster (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
113,986 Da
NCBI Official Full Name
Ectoderm-expressed 4, isoform F
NCBI Official Synonym Full Names
Ectoderm-expressed 4
NCBI Official Symbol
Ect4
NCBI Official Synonym Symbols
anon-WO0118547.272; CG13680; CG13681; CG34373; CG43119; CG7905; CG7915; DmelCG43119; dsarm; dSarm; ect4; Ect4/SARM
NCBI Protein Information
CG43119 gene product from transcript CG43119-RI
UniProt Protein Name
Sterile alpha and TIR motif-containing protein 1
UniProt Gene Name
Ect4
UniProt Synonym Gene Names
dsarm; dSarm
Uniprot Description
Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury (PubMed:22678360). Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site (PubMed:22678360). Involved in the down-regulation of the tracheal immune response to Gram-negative bacteria (PubMed:22022271). This is likely by mediating Tollo signaling in the tracheal epithelium (PubMed:22022271).
Research Articles on Ect4
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Product Notes
The Ect4 ect4 (Catalog #AAA1370273) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 687-981. Partial. The amino acid sequence is listed below: VPLWSVEDVQ EWVKQIGFND YIDKFNESQV DGDLLLKLNQ DNLRADIGIG NGILLKRFER ELQNLKRMAD YSSKDTAKMH QFLSEIGTDY CTYTYAMLNA GIDKCALPHV NEDMLMTECG IHNSIHRLRI LNAVKNLENS LPSSSEENMA KTLDVFVSYR RSNGSQLASL LKVHLQLRGF SVFIDVERLE AGKFDNGLLN SIRQAKNFVL VLTPDALHRC INDEDCKDWV HREIVAALNS NCNIIPIIDQ QFDWPEVERL PEDMRSVAHF NGVNWIHDYQ DACIDKLERF LRGEK. It is sometimes possible for the material contained within the vial of "Sterile alpha and TIR motif-containing protein 1 (Ect4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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