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Endothelin Converting Enzyme 1 (ECE1) Recombinant Protein | ECE1 recombinant protein
Recombinant Endothelin Converting Enzyme 1 (ECE1)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-APAIN WLPFLNTIFY PVEINESEPI VVYDKEYLRQ VSTLINNTDK CLLNNYMMWN LVRKTSSFLD QRFQDADEKF MEVMYGTKKT CIPRWKFCVS DTENNLGFAL GPMFVKATFA EDSKNIASEI IMEIKKAFEE SLSTLKWMDE ETRRSAKEKA DAIYNMIGYP NFIMDPKELD KVFNDYTAVP DLYFENAMRF FNFSWRVTAD QLRKAPNRDQ WSMTPPMVNA YYSPTKNEIV FPAGILQAPF YTRSSPN
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.
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NCBI and Uniprot Product Information
Uniprot Description
ECE1: Converts big endothelin-1 to endothelin-1. Defects in ECE1 are a cause of Hirschsprung disease cardiac defects and autonomic dysfunction (HSCRCDAD). It is a form of Hirschsprung disease with skip-lesions defects, craniofacial abnormalities and other dysmorphic features, and autonomic dysfunction. Belongs to the peptidase M13 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Protease; Cell surface; Membrane protein, integral; EC 3.4.24.71; Vesicle
Cellular Component: Golgi apparatus; cell surface; lysosomal membrane; early endosome; integral to membrane; secretory granule; membrane; perinuclear region of cytoplasm; plasma membrane; cytoplasmic vesicle; vesicle; endosome; external side of plasma membrane
Molecular Function: peptidase activity; protein homodimerization activity; metallopeptidase activity; hydrolase activity; metalloendopeptidase activity; metal ion binding; endopeptidase activity
Biological Process: pharyngeal system development; regulation of vasodilation; apoptosis; heart development; peptide hormone processing; ear development; proteolysis; regulation of blood pressure; positive regulation of G-protein coupled receptor protein signaling pathway; positive regulation of cAMP biosynthetic process; response to hypoxia; protein processing; hormone catabolic process; embryonic digit morphogenesis; positive regulation of receptor recycling
Research Articles on ECE1
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Product Notes
The ECE1 ece1 (Catalog #AAA2009887) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Endothelin Converting Enzyme 1 (ECE1) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the ECE1 ece1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF-APA IN WLPFLNTIFY PVEINESEPI VVYDKEYLRQ VSTLINNTDK CLLNNYMMWN LVRKTSSFLD QRFQDADEKF MEVMYGTKKT CIPRWKFCVS DTENNLGFAL GPMFVKATFA EDSKNIASEI IMEIKKAFEE SLSTLKWMDE ETRRSAKEKA DAIYNMIGYP NFIMDPKELD KVFNDYTAVP DLYFENAMRF FNFSWRVTAD QLRKAPNRDQ WSMTPPMVNA YYSPTKNEIV FPAGILQAPF YTRSSPN. It is sometimes possible for the material contained within the vial of "Endothelin Converting Enzyme 1 (ECE1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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