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ESX-1 secretion system protein eccB1 (eccB1) Recombinant Protein | eccB1 recombinant protein

Recombinant ESX-1 secretion system protein eccB1 (eccB1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
ESX-1 secretion system protein eccB1 (eccB1); Recombinant ESX-1 secretion system protein eccB1 (eccB1); eccB1 recombinant protein
Ordering
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-480
Sequence
MGLRLTTKVQVSGWRFLLRRLEHAIVRRDTRMFDDPLQFYSRSIALGIVVAVLILAGAALLAYFKPQGKLGGTSLFTDRATNQLYVLLSGQLHPVYNLTSARLVLGNPANPATVKSSELSKLPMGQTVGIPGAPYATPVSAGSTSIWTLCDTVARADSTSPVVQTAVIAMPLEIDASIDPLQSHEAVLVSYQGETWIVTTKGRHAIDLTDRALTSSMGIPVTARPTPISEGMFNALPDMGPWQLPPIPAAGAPNSLGLPDDLVIGSVFQIHTDKGPQYYVVLPDGIAQVNATTAAALRATQAHGLVAPPAMVPSLVVRIAERVYPSPLPDEPLKIVSRPQDPALCWSWQRSAGDQSPQSTVLSGRHLPISPSAMNMGIKQIHGTATVYLDGGKFVALQSPDPRYTESMYYIDPQGVRYGVPNAETAKSLGLSSPQNAPWEIVRLLVDGPVLSKDAALLEHDTLPADPSPRKVPAGASGAP
Sequence Length
480
Species
Mycobacterium tuberculosis
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for eccB1 recombinant protein
eccB1

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,093 Da
NCBI Official Full Name
hypothetical protein Rv3869
UniProt Protein Name
ESX-1 secretion system protein eccB1
UniProt Gene Name
eccB1
UniProt Synonym Gene Names
T7SS protein eccB1
UniProt Entry Name
ECCB1_MYCTU

Uniprot Description

Function: Probably part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10). Ref.3

Subunit structure: Part of the ESX-1 / type VII secretion system (T7SS), which is composed of cytosolic and membrane components

Probable. Ref.3

Subcellular location: Cell membrane; Single-pass membrane protein

Potential.

Disruption phenotype: Disruption abolishes EsxA and EsxB secretion, which results in a lack of antigen specific immunogenicity and leads to attenuated virulence. Does not affect their expression. Ref.3

Sequence similarities: Belongs to the EccB family.

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Product Notes

The ESX-1 secretion system protein eccB1 (eccB1) eccb1 (Catalog #AAA1132177) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-480. The amino acid sequence is listed below: MGLRLTTKVQ VSGWRFLLRR LEHAIVRRDT RMFDDPLQFY SRSIALGIVV AVLILAGAAL LAYFKPQGKL GGTSLFTDRA TNQLYVLLSG QLHPVYNLTS ARLVLGNPAN PATVKSSELS KLPMGQTVGI PGAPYATPVS AGSTSIWTLC DTVARADSTS PVVQTAVIAM PLEIDASIDP LQSHEAVLVS YQGETWIVTT KGRHAIDLTD RALTSSMGIP VTARPTPISE GMFNALPDMG PWQLPPIPAA GAPNSLGLPD DLVIGSVFQI HTDKGPQYYV VLPDGIAQVN ATTAAALRAT QAHGLVAPPA MVPSLVVRIA ERVYPSPLPD EPLKIVSRPQ DPALCWSWQR SAGDQSPQST VLSGRHLPIS PSAMNMGIKQ IHGTATVYLD GGKFVALQSP DPRYTESMYY IDPQGVRYGV PNAETAKSLG LSSPQNAPWE IVRLLVDGPV LSKDAALLEH DTLPADPSPR KVPAGASGAP. It is sometimes possible for the material contained within the vial of "ESX-1 secretion system protein eccB1 (eccB1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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