IP-10 (CXCL10) active protein
Rat IP-10 (CXCL10)
Gene Names
Cxcl10; IP-10; Scyb10
Reactivity
Rat
Purity
> 98% by SDS-PAGE & HPLC analyses
Synonyms
IP-10 (CXCL10); Rat IP-10 (CXCL10); gamma-Interferon inducible protein 10; CXCL10; crg-2; IP-10 (CXCL10) active protein
Host
E Coli
Reactivity
Rat
Purity/Purification
> 98% by SDS-PAGE & HPLC analyses
Form/Format
Lyophilized
Sequence
IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMK KNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP
Sequence Length
98
Biological Activity
Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10.0-50.0 ng/ml.
Related Product Information for IP-10 (CXCL10) active protein
IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.
Product Categories/Family for IP-10 (CXCL10) active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,729 Da
NCBI Official Full Name
C-X-C motif chemokine 10
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 10
NCBI Official Symbol
Cxcl10
NCBI Official Synonym Symbols
IP-10; Scyb10
NCBI Protein Information
C-X-C motif chemokine 10; gamma-IP10; protein Mob-1; small-inducible cytokine B10; interferon-inducible protein 10; interferon-inducible cytokine IP-10; 10 kDa interferon gamma-induced protein; small inducible cytokine B subfamily (Cys-X-Cys) member 10; small inducible cytokine B subfamily (Cys-X-Cys), member 10
UniProt Protein Name
C-X-C motif chemokine 10
UniProt Gene Name
Cxcl10
UniProt Synonym Gene Names
Inp10; Mob1; Scyb10; Gamma-IP10; IP-10
UniProt Entry Name
CXL10_RAT
NCBI Description
induces DNA synthesis, cell proliferation, and cell migration in vascular smooth muscle cells; may play a role in vascular remodeling [RGD, Feb 2006]
Uniprot Description
Function: In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development
By similarity.
Subcellular location: Secreted.
Tissue specificity: Spleen.
Induction: By oncogenic Ras and serum growth factors. The oncogenic induction is constitutive whereas the serum induction is transient.
Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
Research Articles on IP-10 (CXCL10)
Similar Products
Product Notes
The IP-10 (CXCL10) cxcl10 (Catalog #AAA691814) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Rat IP-10 (CXCL10) reacts with Rat and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMK KNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP. It is sometimes possible for the material contained within the vial of "IP-10 (CXCL10), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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